Dr Peter McCullough: How to Measure Your Spike Protein Antibody (2026)

Dr. McCullough explained (1) that the spike protein is an engineered, synthetic molecule roughly 1,200 amino acids long and resistant to degradation by the body’s normal proteases. He described how the protein was modified in laboratory settings (notably at the Wuhan Institute of Virology) to tightly bind to the ACE2 receptor, which is found throughout the body—in the lungs, heart, endothelium, kidneys, and brain. Because this receptor regulates angiotensin metabolism, older individuals with fewer ACE2 sites catabolize the spike less efficiently, leading to worse outcomes. Whether introduced by infection or by genetic‑code‑based vaccines, McCullough asserted, the persistent spike damages tissues directly and through chronic inflammation, micro‑clotting, and autoimmune cross‑reactivity.



He cited more than 300 papers documenting spike deposits in the heart, brain, and vascular tissue, relating these findings to post‑vaccine myocarditis, strokes, and clotting disorders. A chief diagnostic step, he said, is LabCorp’s quantitative anti‑spike antibody test run on the Roche‑Elecsys system; titers <1,000 U/mL suggest low risk, whereas high persistent titers (>10,000 U/mL) imply continued spike stimulation. Combined cardiac markers, such as troponin, BNP, galectin‑3, and D‑dimer, help clinicians assess myocardial inflammation and microthrombosis.McCullough emphasized certain non‑pharmaceutical interventions to “mobilize and clear” the protein: regular sweating (via exercise, outdoor heat, or infrared sauna) to eliminate spike and residual mRNA through skin and sweat glands, and hyperbaric oxygen therapy to enhance oxygenation and possibly alter spike conformation for clearance. He also endorsed modalities that improve micro‑circulation, such as pulsed‑electromagnetic‑field (PEMF) or Beamer devices.

The central focus was the McCullough Protocol Base Spike Detoxification,™ comprising three natural compounds shown in preclinical research to degrade or neutralize spike protein:
  1. Nattokinase (2,000–8,000 fibrinolytic units per dose) – an enzyme from fermented soy that dissolves fibrin and spike aggregates;
  2. Bromelain (500 mg) – pineapple‑stem protease with anticoagulant and anti‑inflammatory effects;
  3. Curcumin (500–1,000 mg, enhanced with piperine or liposomal form) – turmeric’s active polyphenol supporting inflammation resolution and hepatic detoxification.

Taken twice daily on an empty stomach for 9–12 months (longer for heavily vaccinated or long‑COVID patients), this triad forms the backbone of The Wellness Company’s Ultimate Spike Detox supplement. McCullough reported thousands of clinical users and minimal adverse events, warning only of potential bleeding when combined with prescription anticoagulants. Adjunctive options include N‑acetylcysteine to support glutathione, hydroxychloroquine for autoimmune suppression, and short courses of ivermectin or longer-term colchicine when indicated.

Related: Spike Protein Syndrome Treatment: 9 Case Reports with Clinical Protocols (2026 Update)

How to Measure Your Spike Protein Antibody?

In clinic today I want to address the most common question I get from patients, “have I been exposed to the SARS-CoV-2 Spike protein through infection, shedding, or vaccination, and what should I do about it?”



This video will explain that you can now take matters into your own hands and order a Spike protein antibody test from Labcorp Labs On Demand and get the results within a few days.

Here is a quick guide of interpretation of your results:
  • <1000 U/ml very low level past exposure, negligible risks
  • 1000-5000 U/ml symptoms or problem could be related to Spike protein
  • >5000 U/ml Spike protein likely circulating in your bloodstream
  • 10,000-25,000 U/ml very high risk for cardiac damage, blood clots, neurologic problems, autoimmunity, and potentially cancer
Remember the antibodies are an indirect reflection of Spike protein and do not change quickly. My advice is not to check the test again for a year. Above is one of my patients who has resolved his Spike syndrome with detoxification and you can see he has had a substantial drop in his Spike antibodies.

What can be done about high levels? The answer for most is the Ultimate Spike Detox from The Wellness Company. This is the only scientifically supported combination product following the principles of McCullough Protocol Base Spike Detoxification.



In my clinical practice I have witnessed rewarding reductions in Spike antibody levels and resolution of long-COVID and vaccine injury syndromes over a year or longer on the Ultimate Spike Detox. For antibody levels <1000 U/ml and concerns over ongoing exposures, I recommend Spike Support from The Wellness Company.



Please consider taking the first step and get your Spike antibody measured today and check out The Wellness Company for all of it’s long-COVID products.

Sources:


Other Spike Antibody Tests (Alternatives)

You can also order a Spike antibody (Covid-19 antibody) test from healthlabs.com to assess your risk and establish a baseline before and after starting any anti-spike protein protocol.

Another option is Attomarker's COVID Antibody Spectrum Test. Although the test is now available for sample collection in the US, the actual testing is still performed in the UK (United Kingdom). Please note that the test report takes about 2 to 3 weeks to arrive (X.com). The COVID Antibody Spectrum Test measures antibody levels & quality to Spike variants. Mapped with variant prevalence & your medical history, it offers insights into your immune profile, and has helped people with long COVID explore treatment pathways.

Conclusion

McCullough urged practitioners to recognize the persistent spike protein as the driver of post‑COVID syndromes and “vaccine injury,” and called for empirical, integrative solutions in the absence of federal research funding.


References:
  1. Dr. Peter McCullough and Dr. Michael Gaeta. https://www.americaoutloud.news/dr-mcculloughs-spike-protein-detox-protocol-explained/ (2026)
  2. Washington Guardian – “Ultimate Spike Detox: The Wellness Company’s Signature Formula for Cellular Defense,” Jan 2, 2025.
  3. McCullough P.A., et al. “Clinical Rationale for SARS‑CoV‑2 Base Spike Protein Detoxification in Post‑COVID‑19 and Vaccine Injury Syndromes,” Journal of American Physicians and Surgeons 28(3):90‑93 (2023).

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