Immune Systems Advisor

Paxlovid vs Remdesivir vs Monoclonal Antibody, what's the difference? If you are confused about the recommendations made by different professional groups for the COVID-19 pandemic, you've come to the right place.   Most people with COVID-19 will experience a mild illness, and they’ll be able to take care of themselves at home. But some—especially those with  underlying health conditions —could benefit from one of several COVID-19 treatments. Some of these are available in pill form and others are given intravenously or by injection—and all of them must be prescribed by a health care provider. As of the week ending August 5, 2023, the Omicron EG.5 variant and XBB sub-variants represent more than 70% of the SARS-CoV-2 variants currently circulating in the United States,  according  to the CDC.  In this article, we will do a roundup and cover 3 popular anti-viral treatments i.e. Remdesivir, Paxlovid and Monoclonal Antibodies. Pa...

The U.S. Food and Drug Administration (FDA) on July 14, 2023   approved Veklury , also known as remdesivir, to treat COVID-19 in people with severe renal impairment, including dialysis, despite data showing the drug   increases the risk   of kidney failure. Remdesivir is an antiviral medication that targets the RNA in viruses to prevent replication. The FDA first  authorized remdesivir  for emergency use in May 2020 to treat people with severe COVID-19. It has since been approved for adults and children as young as 28 days who weigh at least 6.6 pounds. This image shows a 3D print of a spike protein of SARS-CoV-2—the virus that causes COVID-19—in front of a 3D print of a SARS-CoV-2 virus particle. (Courtesy of NIAID/RML) Remdesivir is the first and only FDA-approved antiviral COVID-19 treatment for people with renal disease. The U.S. approval follows the European Commission’s decision on June 26 to extend the approved use of Veklury to treat COVID-19 in people w...

Most people with COVID-19 will experience a mild illness, and they’ll be able to take care of themselves at home. But some—especially those with  underlying health conditions —could benefit from one of several COVID-19 treatments. Some of these are available in pill form and others are given intravenously or by injection—and all of them must be prescribed by a health care provider. In this article, we will do a roundup and cover 3 popular anti-viral treatments i.e. Remdesivir, Bebtelovimab and Sotrovimab. Bebtelovimab (Monoclonal Antibody) Bebtelovimab is an US FDA-authorized investigational monoclonal antibody treatment that was developed by Eli Lilly.  Is bebtelovimab effective against omicron: Data showing bebtelovimab’s efficacy against Omicron and its BA.2 subvariant prompted the FDA to authorize the drug through an EUA. A lab study published in July 2022 ( NEJM ) using the live-virus Focus Reduction Neutralization Testing (FRNT) method revealed that bebtelovima...