Immune Systems Advisor

Mayumi Matsuda et al. Immunological Medicine Published online: 16 Apr 2024 PMID:  38627989 Abstract  Vaccines against coronavirus disease 2019 (COVID-19) have been distributed in most countries for the prevention of onset and aggravation of COVID-19. Recently, there have been increasing numbers of reports on new-onset autoimmune and autoinflammatory diseases following COVID-19 vaccination, however, only little information is available on the long-term safety of these vaccines. Here, we experienced three cases of new-onset rheumatic diseases following COVID-19 vaccination, one case each of rheumatoid arthritis (RA), anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and systemic lupus erythematosus (SLE). The symptom onset ranged from one day to a few days following vaccination. The patients of AAV and SLE were treated successfully with glucocorticoid therapy, and the patient of RA died due to COVID-19. In the literature review of new-onset rheumatic diseas...

A bombshell new study has confirmed that surging cases of several once-rare forms of “debilitating neurological disorders” are being caused by Covid mRNA shots. The discovery was made by an international group of neurology-focused researchers. The team, made up of leading researchers in the United States and Kenya, sought to investigate the links between Covid mRNA injections and recent spikes in reports of  autoimmune encephalitis  (AE),  neuromyelitis optica spectrum disorder  (NMOSD), and  myelin oligodendrocyte glycoprotein antibody-associated disease  (MOGAD). All three are described as “complex and debilitating neurological disorders.” For the study, the researchers used data from the U.S. Centers for Disease Control and Prevention’s (CDC) Vaccine Adverse Event Reporting System (VAERS). VAERS has recorded surging reports of AE, NMOSD, and MOGAD since the Covid mRNA injections were rolled out for public use in early 2021. As part of this investigation,...

Dr. Clarice Saba, an otorhinolaryngologist in Brazil, developed sudden hearing loss in her right ear a week after receiving her first dose of the COVID-19 adenovirus vaccine. “I did all the exams and could not find any other reason other than because of the shots,” she told The Epoch Times. This image shows a 3D print of a spike protein of SARS-CoV-2—the virus that causes COVID-19—in front of a 3D print of a SARS-CoV-2 virus particle. (Courtesy of NIAID/RML) Several studies have linked sudden hearing loss to the vaccine, with the most comprehensive study coming from France . Four hundred cases of post-vaccine sudden sensorineural hearing loss were evaluated, with 345 medical reports assessed by two audiology experts for potential causality. “[Sudden sensorineural hearing loss] after COVID-19 mRNA vaccines are very rare adverse events,” the French authors concluded, adding that these rare adverse events “do not call into question the benefits of mRNA vaccines but deserve to be known giv...

A published medical report out of Mexico details two cases of healthy, female health care workers who got COVID-19 vaccines and, three days later, developed “thyroid hyperactivity, suppressed thyroid-stimulating hormone, and elevated antithyroid antibodies.” They were both diagnosed with vaccine-induced Graves’ disease. According to the authors who wrote up the cases, “autoimmune/inflammatory syndrome induced by [vaccine] adjuvants (ASIA), described for the first time a decade ago, is triggered by several adjuvants (a substance that enhances the antigen-specific immune response) and includes the following conditions: Gulf War syndrome, siliconosis, macrophagic myofasciitis syndrome, and postvaccination phenomena.” One of the victims described was a 28-year old medical resident with no history of autoimmune disorder . Three days after getting the Pfizer/BioNTech vaccine,...

Some vaccinated and COVID-infected people are reportedly being diagnosed with a new type of disease called VEXAS syndrome—an autoinflammatory disease discovered in 2020. Many people are familiar with autoimmune diseases, often caused by dysfunction among the adaptive immune cells, while problems within the innate immune system often cause autoinflammatory diseases. VEXAS syndrome—short for vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic syndrome—is caused by mutations in the innate immune cells, a somatic mutation in the UBA1 gene found on the X chromosome. Somatic mutations cannot be inherited, meaning individuals acquire this mutation later in life. The mutation affects the stem cells in the bone marrow. The cells mature into specialized immune cells that circulate within the bloodstream. Immune cells carrying the UBA1 mutation are highly inflammatory, and once enough of them accumulate, patients start developing symptoms. In April 2023, a French paper reported on a 76-year...