Immune Systems Advisor

Dr. Peter McCullough is an internist, cardiologist, epidemiologist, a full professor of medicine at Texas A&M College of Medicine in Dallas, USA. He also has a master's degree in public health and is known for being one of the top five most-published medical researchers in the United States and is the editor of two medical journals. McCullough Protocol 2022 Update: Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections: A Phase 2 Randomized Clinical Trial ( JAMA 2025 ) Everyone is familiar with nasal and oral swab testing for COVID-19. It should be obvious the virus is replicating in the nose, and with Omicron, the speed of replication has become much greater than the prior strains of the virus. Thus, there is a wonderful opportunity to reduce viral replication, in fa...

Do nasal sprays actually work against COVID-19? There has been quite a lot of activities in the COVID nasal spray space.  Two old-school nasal sprays—one antihistamine (azelastine) and one seaweed-derived barrier (iota-carrageenan)—now have randomized human data suggesting they can lower the risk of infection when used regularly during high exposure events (such as air travel, parties, etc). Below, we look at some of the best nasal sprays for COVID-19 and summaries of the rationale and evidence for each category. Do note that some of them are available as an over-the-counter medication but some are still under clinical trial stage. Best Nasal Sprays for COVID-19 There are lots of great nasal sprays out there, and this list is by no means complete. We’ve included nasal sprays with proven anti-COVID-19 ingredient, you can buy over the counter or online. 1. Povidone   Iodine Nasal Spray   and COVID-19 Povidone...

Please enjoy this continuing medical education lecture delivered at 40th Cellular Detoxification Conference sponsored by International College of Integrative Medicine in Indianapolis, Indianana, on September 7, 2024. There are no medicine grand rounds or primary care conferences addressing this topic. It is a white space in medicine where no academic medical center has a fundamental approach to handling about 5-10% of the population suffering from post-acute sequalae after recurrent SARS-CoV-2 infection or COVID-19 infection. Both load the body with pathogenic Spike protein which incites inflammation, oxidative stress, coagulation, and all the downstream effects that result in symptoms. BSD=Base Spike Detoxification Because I have taken the ultimate accountability for McCullough Protocol Base Spike Detoxification (BSD) by publishing and copyrighting it in my own name, I can tell you first hand I get feedback about perceived safety and efficacy on a regular basis from all ov...

By OneDayMD | Updated 2026 Long COVID has evolved from a vague post-viral syndrome into one of the most complex chronic conditions in modern medicine. Millions of patients continue to experience fatigue, brain fog, shortness of breath, and cardiovascular symptoms months—or years—after acute infection. This article cuts through the noise. 👉 We present a clean, evidence-aligned Long COVID protocol —designed to maximize benefit while minimizing risk. 👉 Built from clinical data (2020–2026), real-world practice, and emerging pathophysiology. Understanding Long COVID: Not One Disease Long COVID (also called post-acute sequelae of SARS-CoV-2 infection, or PASC) is not a single condition . It is a spectrum involving: Immune dysregulation Autonomic nervous system dysfunction Endothelial injury Mitochondrial dysfunction Possible viral persistence (subset of patients) There is strong overlap with conditions like: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Postural Orthostatic Tachycardi...

For years, clinicians and patients have described a disturbing pattern — cancers appearing suddenly, growing at unexpected speed, or diseases thought stable returning aggressively within weeks or months. A sudden rise in younger people with early onset cancers which are more aggressive with more (and unusual) genetic change has been increasingly noted - colorectal, breast and GI tract cancers seem to lead the way. Some called them “turbo cancers”. In oncology, the phenomenon is known as hyper-progression: cancers that accelerate far more rapidly than expected. Early on, these reports were ignored. They surfaced as scattered cases — isolated anecdotes that were easy to dismiss. One of the first to speak publicly was Belgian immunologist Michel Goldman, whose story was published in The Atlantic in 2022. He believed the Covid-19 vaccine may have accelerated his lymphoma. Shortly after vaccination and boosting, he developed swollen lymph nodes, fatigue and night sw...