Immune Systems Advisor

Immune Systems Advisor · Integrative Medicine White Paper · Open Access Authors: OneDayMD Editorial Team (synthesis and editorial adaptation) · Original protocols: Marik P, Kory P (IMA/FLCCC, 2022–2024); McCullough PA (Cureus, 2023) · Published: March 2023 · Last updated: June 2026 · DOI: n/a (educational synthesis) Evidence Tier Key:   TIER 1 RCT / systematic review   TIER 2 Observational / cohort   TIER 3 In vitro / mechanistic   TIER 4 Expert consensus / clinical observation ⚠ Medical Disclaimer — Please Read First. This article is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The protocols described involve supplements with significant anticoagulant activity. Always consult a licensed physician before starting, especially if you take blood thinners, are pregnant or breastfeeding, have a bleeding disorder, or...

A clinician-developed regimen of nattokinase, bromelain, and curcumin for clearing persistent SARS-CoV-2 spike protein — with dosing, safety guidance, monitoring, and full FAQ.   Editorial Team   |  Originally published March 2023  |  Last updated June 30, 2026  |  Reviewed against published literature and Dr. McCullough's 2025 clinical updates ⚠️ Medical Disclaimer — Please Read First This article is for  educational purposes only  and does not constitute medical advice, diagnosis, or treatment. The Base Spike Detox protocol involves supplements with significant anticoagulant activity. Always consult a licensed physician before starting , especially if you are taking blood thinners, are pregnant or breastfeeding, have a bleeding disorder, or are treating a child. For a virtual consultation with a physician familiar with this protocol, vis...