Immune Systems Advisor

Medical Disclaimer: The information provided in this article is for educational and research purposes only and does not constitute formal medical advice. Post-Acute Sequelae of COVID-19 (PASC) is a complex medical condition. Always consult a licensed healthcare professional before starting any new dietary supplement or treatment protocol. Federal data published by the U.S. CDC indicates that approximately 17.9% of adults who previously contracted COVID-19 continue to experience persistent symptoms of Long COVID (Post-Acute Sequelae of SARS-CoV-2, or PASC). Clinical research shows that post-viral chronic illness disproportionately impacts females, individuals who experienced severe initial infections, and those with pre-existing metabolic conditions. If you are struggling with debilitating fatigue, brain fog, chest discomfort, or autonomic dysfunction three months or more after infection, you are navigating post-COVID syndrome. Understanding the biological d...

Melatonin is a hormone synthesized in your pineal gland and several other organs, 1   indeed in most cells, including human lung monocytes and macrophages, as it is actually synthesized in your mitochondria. 2 While most well-known as a natural sleep regulator, melatonin also has many other important functions. 3  Notably, it plays an important role in cancer prevention 4  and may prevent or improve certain autoimmune diseases, such as Type 1 diabetes. 5 It also has anticonvulsant and antiexcitotoxic properties, 6  and is a potent antioxidant 7  with the rare ability to enter your mitochondria, 8  where it helps prevent mitochondrial impairment, energy failure and the death of mitochondria damaged by oxidation. 9  It also: Boosts immune function Helps recharge glutathione 10  (and glutathione deficiency has been linked to COVID-19 severity) May improve the treatment of certain bacterial diseases,...

Two key studies have identified the role melatonin plays in reducing the risk of a positive test for COVID-19 1   and lowering the incidence of severe symptoms. 2   Melatonin was first discovered in 1958 by Dr. Aaron Lerner, a dermatologist, who was able to isolate it from the pineal gland in a cow. 3 Scientists began studying melatonin in the 1980s and by the 1990s it received more attention. Research data showed that melatonin influences a number of different bodily processes, including calcium-dependent metabolism, immune modulation and restraining tumor growth. Although melatonin is produced in a variety of tissues, the major source is the pineal gland in the brain. This is a tiny endocrine gland found in the center of the brain. One of the initial functions is likely as a free radical scavenger. Interestingly, melatonin also functions in plants to reduce oxidative stress and promote seed germination and growth. 4 The necessary precursor in plants and animals is tryptophan...