The Cancer Prevention Master Guide (2026 Edition): I-PREVENT, the ROOT Protocol & the Complete Five-Layer Framework
Medically reviewed and updated by the OneDayMD Editorial Team | Dr. Frank Yap, MD, Medical Reviewer | Master guide edition published September 2026 | Consolidates and supersedes two prior standalone articles (see Source & Update Note below) Quick Answer: This master guide consolidates OneDayMD's I-PREVENT Cancer Protocol and Dr. Paul Marik and Dr. Justus Hope's ROOT Protocol into one five-layer, ebook-style framework for cancer prevention in healthy or at-risk adults — not a treatment protocol. Layer 1 is diet, metabolic health, and lifestyle, including environmental-exposure and sleep hygiene. Layers 2–3 are food-derived nutraceuticals (EGCG, curcumin, vitamin D3, omega-3, berberine, sulforaphane, vitamin C, magnesium, zinc, garlic, melatonin, and more), ranked from strongest human-trial evidence to broader supporting data. Layer 4 is an optional Aged Garlic Extract upgrade. Layer 5 is Root 9 — the prescription drugs celecoxib, ivermectin, and mebendazole — ...