Cold and Flu Season 2026–2027: Symptoms, Prevention, Treatment and the Oseltamivir Paradigm Shift
Cold and flu season is not simply about having a thermometer and a box of cold medicine ready. The modern respiratory-virus landscape includes influenza, COVID-19, RSV and other viruses—and the evidence on how we should treat severe influenza is changing. Updated September 2026 • Evidence reviewed from CDC, WHO, Australian Living Evidence Collaboration and the 2026 REMAP-CAP influenza antiviral results Key update for 2026: A major REMAP-CAP randomized trial found that oseltamivir did not improve 90-day survival in critically ill patients with influenza and crossed a prespecified inferiority threshold. Australian interim guidance now recommends against oseltamivir in critically ill adults. This finding is highly important—but it does not mean that oseltamivir should be stopped in every person with influenza. Contents Why cold and flu season matters Cold vs flu: what is the difference? Common symptoms Who is at higher risk? Ho...