Immune Systems Advisor

Medically reviewed and updated by the OneDayMD Editorial Team | Dr. Frank Yap, MD, Medical Reviewer | Master guide edition published September 2026 | Consolidates and supersedes two prior standalone articles (see Source & Update Note below) Quick Answer: This master guide consolidates OneDayMD's I-PREVENT Cancer Protocol and Dr. Paul Marik and Dr. Justus Hope's ROOT Protocol into one five-layer, ebook-style framework for cancer prevention in healthy or at-risk adults — not a treatment protocol. Layer 1 is diet, metabolic health, and lifestyle, including environmental-exposure and sleep hygiene. Layers 2–3 are food-derived nutraceuticals (EGCG, curcumin, vitamin D3, omega-3, berberine, sulforaphane, vitamin C, magnesium, zinc, garlic, melatonin, and more), ranked from strongest human-trial evidence to broader supporting data. Layer 4 is an optional Aged Garlic Extract upgrade. Layer 5 is Root 9 — the prescription drugs celecoxib, ivermectin, and mebendazole — ...

Medical Disclaimer: The information provided in this article is for educational and research purposes only and does not constitute formal medical advice. Post-Acute Sequelae of COVID-19 (PASC) is a complex medical condition. Always consult a licensed healthcare professional before starting any new dietary supplement or treatment protocol. Federal data published by the U.S. CDC indicates that approximately 17.9% of adults who previously contracted COVID-19 continue to experience persistent symptoms of Long COVID (Post-Acute Sequelae of SARS-CoV-2, or PASC). Clinical research shows that post-viral chronic illness disproportionately impacts females, individuals who experienced severe initial infections, and those with pre-existing metabolic conditions. If you are struggling with debilitating fatigue, brain fog, chest discomfort, or autonomic dysfunction three months or more after infection, you are navigating post-COVID syndrome. Understanding the biological d...

A clinician-developed regimen of nattokinase, bromelain, and curcumin for clearing persistent SARS-CoV-2 spike protein — with dosing, safety guidance, monitoring, and full FAQ.   Editorial Team   |  Originally published March 2023  |  Last updated August 2026  |  Reviewed against published literature and Dr. McCullough's 2025 clinical updates ⚠️ Medical Disclaimer — Please Read First This article is for  educational purposes only  and does not constitute medical advice, diagnosis, or treatment. The Base Spike Detox protocol involves supplements with significant anticoagulant activity. Always consult a licensed physician before starting , especially if you are taking blood thinners, are pregnant or breastfeeding, have a bleeding disorder, or are treating a child. For a virtual consultation with a physician familiar with this protocol, visit...