Immune Systems Advisor

By OneDayMD Editorial Team | Originally published May 2023 | Last updated October 2026 | Sources reviewed through October 2026 Quick Answer The FLCCC/IMA I-CARE Flu and RSV protocol is a home regimen of nasal and mouth antiseptics, supplements and off-label drugs. Most components are supported by laboratory or expert-opinion evidence, not influenza trials. The best-evidenced treatments for influenza are prescription antivirals started early: oseltamivir for hospitalized patients and baloxavir or oseltamivir for high-risk outpatients. Seek care promptly if you are high-risk or struggling to breathe. What changed in this update (October 2026) Fixed copy-paste wording that described the protocol as a COVID-19 guide. Replaced the claim that Tamiflu has “no antiviral properties.” Oseltamivir is a direct-acting neuraminidase inhibitor, and the 2025 paper is in JAMA Ne...

Early treatment is critical and the most important factor in managing this disease. COVID-19 is a clinical diagnosis; a confirmed antigen or PCR test is not required. Treatment should be initiated immediately after the onset of flu-like symptoms. The multiple therapies and drugs in this protocol have different mechanisms of action and work synergistically during various phases of the disease. About I-CARE Protocol The information in this document is our recommended approach to COVID-19 based on the best (and most recent) literature. It is provided as guidance to healthcare providers worldwide on the early treatment of COVID-19. Patients should always consult with their provider before starting any medical treatment. Updates:  The Stratus Variant (XFG): Symptoms, Global Spread, and Impact in Late 2025 Note: According to Dr Pierre Kory, "...highlighting his objectivity, while Pierre Kory was once the leading advocate for ivermectin to treat COVID, he no longer does as the newer vari...