Cyclosporiasis Outbreak 2026: Cases Top 6,000 in Michigan and 98 hospitalized

Medically reviewed by Editorial Team | Last updated: July 21, 2026

Quick Answer

Cyclosporiasis is a diarrheal illness caused by the parasite Cyclospora cayetanensis, usually picked up from contaminated fresh produce. A large 2026 outbreak has pushed Michigan's case count past 6,000 (102 hospitalized), with additional cases confirmed in states including Ohio, New York, and Texas. The source of contamination has been traced to a lettuce supplier in Mexico. Most healthy people recover, and the antibiotic trimethoprim-sulfamethoxazole (TMP-SMX) is the CDC's recommended treatment.

A fast-moving outbreak of cyclosporiasis — an intestinal infection caused by a microscopic parasite typically carried on fresh produce — has become one of the largest seen in the United States in years. Michigan has borne the brunt of it, but health departments in several other states are reporting cases as investigators work to trace the contamination back to its source.

FDA managed to trace contaminated lettuce back to a lettuce supplier in Mexico. On July 17, 2026, Taylor Farms initiated a recall of all iceberg lettuce sourced from central Mexico. The recall includes iceberg lettuce sold at retail stores and restaurants. It also includes other recalled products distributed to food service customers. A complete list of those products is included in the recall notice. (CDC)


Update (July 19, 2026)Taylor Farms lettuce sample produced false positive for cyclospora, FDA says

PCR testing on stool and immediate treatment with TMP-SMX (e.g, Bactrim) especially in patients with explosive diarrhea.


Below is a consolidated, continuously relevant guide to what's happening, why it matters, and how to protect yourself and your family.

What Is Cyclosporiasis?

Cyclosporiasis is an intestinal illness caused by Cyclospora cayetanensis, a single-celled parasite too small to see without a microscope. Unlike bacteria such as E. coli or Salmonella, Cyclospora has a two-part life cycle: part of it plays out inside the human gut, and part of it takes place out in the environment, where the parasite needs time — typically days to weeks — to mature into a form that can infect someone else. That delay is one reason outbreaks can be so hard to pin down; by the time people get sick, the contaminated batch of produce may be long gone from store shelves.


The illness is seasonal in the United States, showing up most years between spring and early fall, and it is almost always traced to fresh produce imported from regions where Cyclospora is more common in the environment — think leafy greens, fresh herbs, and berries.

The 2026 Outbreak at a Glance

Michigan's outbreak began drawing attention in late June, when a Monroe County cluster of cases came to the health department's notice. Since then, the case count has climbed sharply:

Date Michigan Cases
June 30, 2026~170
July 4, 2026572
July 7, 2026708
July 8, 2026992
July 9, 20261,251
July 10, 20261,562
July 20, 20266,148

Michigan typically logs only around 50 cyclosporiasis cases in an entire year, so this outbreak represents a many-fold increase over baseline. As of the most recent update, cases have been confirmed in roughly 40 counties, with Monroe County reporting the most (215 cases), and 102 patients have required hospitalization. Adults aged 30–39 make up the largest single age group affected. No deaths have been reported. Because Michigan's dashboard updates daily on weekdays, readers should check the state's live outbreak page and the MDHHS Infectious Disease Outbreaks webpage for the newest figures.

Michigan is not alone. According to CDC data cited by state health departments, at least 31 states have reported cyclosporiasis cases since May 1, 2026, though Michigan accounts for the large majority of this year's total. The table below summarizes the other states with notable, publicly confirmed activity:

State Reported Cases Notes
Ohio171 (28 hospitalized)State health director calls it a serious illness that can require emergency care
New York118 (since May 1)Department stresses cases are not spreading person-to-person
Texas~11 (recent)State notes its cyclospora season normally runs May 1–Aug 31
A note on the numbers: The CDC discontinued a requirement in mid-2025 for states to report cyclosporiasis cases to its FoodNet surveillance system, citing other tracking mechanisms. Public health officials have also noted that part of this year's rise may reflect increased clinician awareness and testing rather than transmission alone — though the scale of the Michigan cluster, and its hospitalization count, indicate a genuine active outbreak rather than a reporting artifact alone.
Cases of cyclosporiasis in four states are linked to an outbreak likely caused by iceberg lettuce, the Centers for Disease Control and Prevention said on July 24, 2026.

Investigations linked cyclosporiasis cases in Illinois, Kansas, Oklahoma and Pennsylvania to an ongoing outbreak that previously covered Indiana, Kentucky, Michigan, Ohio and West Virginia, the CDC said.

The total number of confirmed patients is 1,947 across the nine states. Epidemiological investigations and work tracing the sicknesses to specific foods show that iceberg lettuce from Taylor Farms in Mexico was contaminated with the parasite Cyclospora and made the people sick, according to the CDC. Of the patients, 98 reported being hospitalized. No deaths have been reported as of yet.

How the Parasite Spreads

Cyclospora reaches people almost exclusively through food or water contaminated with trace amounts of infected human stool — most often via fresh produce that is eaten raw. Person-to-person spread is considered unlikely, because a newly shed parasite needs days to weeks in the environment before it becomes capable of infecting someone else. That delayed infectivity window is what separates Cyclospora from viruses like norovirus, and it's also why outbreaks tend to trace back to a shared food source rather than to sick coworkers or family members.

Once ingested, the parasite settles into the lining of the small intestine, where it reproduces and damages the gut lining — this is what drives the hallmark watery diarrhea. Eventually, new parasite cells (oocysts) are shed in stool and released back into the environment, restarting the cycle.

“The true number of sick people in this multistate outbreak is likely higher than the number reported, and the outbreak may not be limited to the states with known illnesses,” the CDC said in a statement.

“This is because some people recover without medical care and are not tested for Cyclospora. In addition, recent illnesses may not yet be reported because it can take as long as 6 weeks to determine if a sick person is part of a Cyclospora outbreak. States in this outbreak may report different illness counts on their websites as they may also include probable illnesses. CDC and FDA are only reporting laboratory confirmed cases.”

Symptoms

Symptoms typically begin one week after exposure, though the range can run from two days to two weeks. Not everyone who is infected develops symptoms.

Common Less Common
Frequent, watery, sometimes "explosive" diarrhea (often 5–6 times daily)
Loss of appetite
Bloating and stomach cramps
Fatigue and weight loss
Nausea and vomiting
Low-grade fever
Body aches
Increased gas

Left untreated, symptoms can persist for weeks or even a month or longer, and may improve before relapsing one or more times.

Cyclosporiasis vs. Norovirus

Both illnesses cause diarrhea, nausea, and vomiting through the fecal-oral route, which leads many people to confuse them. The key differences matter for figuring out how you got sick and how long it will last:

Feature Cyclosporiasis Norovirus
CauseParasiteVirus
OnsetSlow (days to ~1 week)Fast (12–48 hours)
DurationDays to weeks, can relapseUsually 1–2 days
Person-to-person spreadUnlikelyHighly contagious
Household clusteringUncommonCommon

Diagnosis

Cyclosporiasis is confirmed through a stool test, but standard stool panels don't automatically screen for it — a healthcare provider generally has to order Cyclospora testing specifically. If you've had persistent diarrhea, especially after eating fresh produce during summer, it's worth explicitly asking your doctor to test for it rather than assuming a routine stool culture will catch it. Early evaluation is particularly important for older adults, young children, pregnant women, and anyone with a weakened immune system, since prompt diagnosis can shorten the course of illness and reduce the risk of complications.

Treatment (CDC Guidance)

Per the CDC's clinical guidance, most people with healthy immune systems will eventually recover from cyclosporiasis even without medication, though the illness can drag on for weeks without treatment. 98 patients have been hospitalized so far (CDC July 24, 2026).

When treatment is given, the first-line option is well established:

Drug CDC-Referenced Dosing
Trimethoprim-sulfamethoxazole (TMP-SMX) — brand names Bactrim, Septra, Cotrim Adults: one double-strength tablet (TMP 160 mg / SMX 800 mg) by mouth, twice daily, for 7–10 days.
Children 2 months–18 years: 8–10 mg/kg TMP and 40–50 mg/kg SMX per day, divided into two doses, for 7–10 days.
This information is provided for general education only — dosing and duration must be determined by your own physician based on your health history.

People who are allergic to or intolerant of TMP-SMX don't currently have a well-proven alternative; the CDC notes that options such as observation with symptomatic care, an antibiotic with only limited evidence against Cyclospora, or formal desensitization under an allergist's supervision may be considered on a case-by-case basis. Notably, the CDC lists several commonly used antimicrobials — including albendazole, azithromycin, doxycycline, metronidazole, and ciprofloxacin — as generally ineffective against this specific parasite based on anecdotal and limited clinical data, which is why self-treating with leftover antibiotics is not advised.

Supportive care matters just as much as medication: staying well hydrated is essential, since the main danger of cyclosporiasis is dehydration from persistent, high-volume diarrhea — a special concern during hot summer weather.

When TMP-SMX cannot be used

There is an urgent need for effective and safer sulfa-free alternative therapeutic agents
considering that trimethoprim-sulfamethoxazole (TMP-SMX), the drug of choice for the treatment of cyclosporiasis, is associated with numerous side effects including bone marrow suppression. Evidence is limited, but options discussed in the literature include:

  1. Nitazoxanide
    • Supported by a small number of case reports and case series.
    • May be considered in patients with sulfonamide allergy.
    • Appears less effective than TMP-SMX.
  2. Ciprofloxacin
    • Has modest activity.
    • Generally considered less effective than TMP-SMX.
    • Sometimes used when TMP-SMX cannot be given.
  3. TMP-SMX desensitization
    • For selected patients with non–life-threatening sulfonamide allergy, supervised desensitization may be considered because no equally effective alternative exists. 
  4. Nano-Curcumin
    • Curcumin (CR) and Curcumin nano-emulsion (CR-NE) may be considered novel agents for treating cyclosporiasis and further studies are needed to investigate the pharmacodynamics and pharmacokinetics of CR-NE. (Parasitologists United Journal 2023)
    • Curcumin and nano-curcumin have not yet been tested in human patients with cyclosporiasis. Their evidence for this infection currently comes from the above animal study. 

Possible Complications

Most cases resolve without lasting effects, but if left unaddressed, cyclosporiasis can occasionally lead to:

  • Significant dehydration from prolonged diarrhea
  • Malabsorption of nutrients
  • Cholecystitis (gallbladder inflammation)
  • Rarely, reactive arthritis or Guillain-Barré syndrome

Who's Most at Risk

Anyone who eats contaminated raw produce can become infected, but the following groups are more likely to experience severe illness or complications and should seek care promptly if symptoms appear:

  • Older adults
  • Young children
  • Pregnant women
  • People with weakened immune systems, including those living with HIV

How to Protect Yourself

Because Cyclospora forms a tough outer shell, washing produce reduces but does not guarantee removal of the parasite — cooking food thoroughly (above 158°F) is the only method confirmed to eliminate it entirely. When eating produce raw, food-safety experts and state health departments recommend:

  1. Wash your hands with soap and water for at least 20 seconds before and after handling food.
  2. Rinse all fruits and vegetables under clean, running water before cutting, cooking, or eating — don't just soak them in a basin.
  3. Cut away any bruised or damaged portions before preparing.
  4. Use a clean produce brush on firm items such as melons and cucumbers.
  5. Buy whole heads of lettuce rather than pre-washed, bagged salad mixes; discard the outer leaves and wash remaining leaves individually.
  6. Separate and thoroughly wash basil and cilantro leaves individually.
  7. For onions, trim the root end, remove the outer layer, and wash thoroughly.
  8. For raspberries and similar hard-to-clean berries, swish them for about a minute in a mixture of three parts water to one part white vinegar, then drain and rinse — or use frozen berries instead.
  9. Cook leafy greens and other produce when possible, rather than eating them raw.

When to See a Doctor

Contact a healthcare provider if you develop diarrhea that lasts more than a few days — particularly during summer or after eating fresh produce — and specifically ask about Cyclospora testing. Seek prompt care if you experience signs of dehydration (dizziness, dark urine, reduced urination), are pregnant, are over 65, are under 5, or have a weakened immune system.

Frequently Asked Questions

What is cyclosporiasis?

It's an intestinal infection caused by the parasite Cyclospora cayetanensis, usually contracted from fresh produce contaminated with trace amounts of infected human stool.

Is cyclosporiasis contagious from person to person?

It's unlikely. The parasite needs days to weeks in the environment after being shed before it can infect someone new, so most transmission happens through contaminated food or water rather than close contact.

How many cyclosporiasis cases have been reported in 2026?

Michigan alone had confirmed 6,148 cases as of July 20, 2026, with 102 hospitalizations. At least 31 states have reported cases since May 1, including Ohio (171 cases), New York (118 cases), and Texas.

What is the treatment for cyclosporiasis?

The CDC recommends trimethoprim-sulfamethoxazole (TMP-SMX, sold as Bactrim or Septra) as the first-line treatment. Most healthy people also recover without medication, though illness can last longer untreated.

How long does cyclosporiasis last?

With treatment, most people improve within a few days. Without treatment, symptoms can last anywhere from a few days to a month or more, and may relapse.

Can washing produce fully prevent infection?

Washing reduces risk but cannot guarantee full removal because the parasite has a resilient outer shell. Cooking produce above 158°F is the only method that reliably kills it.

Have there been any deaths from the 2026 outbreak?

No deaths have been reported as of the most recent updates, though dozens of hospitalizations have occurred, primarily in Michigan and Ohio.

Sources

Related:

This article is for general educational purposes and is not a substitute for professional medical advice, diagnosis, or treatment. Case counts reflect the most recent figures available at time of publication and are subject to change as health departments update their data; always consult your state health department's dashboard for real-time numbers. Never disregard professional medical advice, or delay seeking it, because of something you read here. If you suspect you have cyclosporiasis, contact a licensed healthcare provider.

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