Turbo Cancers on the Rise: 2025 Studies and Updates

By Editorial Team -
A sudden rise in younger people with early onset cancers which are more aggressive with more (and unusual) genetic change has been increasingly noted - colorectal, breast and GI tract cancers seem to lead the way.

New Study Defines Mechanisms of Post-mRNA Vaccine “Turbo Cancer”

Peer-reviewed research from Drs. Paul Marik and Justus Hope links COVID-19 mRNA vaccines to “turbo cancer,” detailing five biological pathways that may drive aggressive, fast-growing cancers.

Dr. Paul Marik, chief scientific officer and co-founder of the Independent Medical Alliance, isn’t one to shy away from hard truths. In his video statement below, accompanying the release of a new peer-reviewed paper, he described what doctors and nurses around the world have been seeing since 2021: more aggressive cancers, affecting younger patients, and returning with a vengeance in people once in remission — often within weeks of a COVID-19 booster shot.

The paper, co-authored with Dr. Justus Hope and published in the Journal of Independent Medicine, takes a term often dismissed as internet hyperbole — “turbo cancer” — and backs it with a detailed, biologically plausible model grounded in tumor biology, immunology, and vaccine safety signal data.

New Study Defines Mechanisms of Post-Vaccine “Turbo Cancer” by Independent Medical Alliance

Peer-reviewed research from Drs. Paul Marik and Justus Hope links COVID-19 mRNA vaccines to “turbo cancer,” detailing five biological pathways that may drive aggressive, fast-growing cancers — and cal

Read on Substack

What Is “Turbo Cancer”?

“Turbo cancer” isn’t a formal medical classification, but it has become clinician shorthand for cancers that behave in ways oncologists find deeply troubling:
  • They present at advanced stages.
  • They progress unusually fast.
  • They are appearing in younger, previously healthy people.
  • They often relapse soon after vaccination in patients once in remission.

“Most oncologists don’t think it exists. Many people think it’s an anti-vax conspiracy. But the truth of the matter is, it’s real.” — Dr. Paul Marik

While mainstream medicine has largely waved off these reports as coincidence, Marik and Hope argue for serious investigation, noting that the timing and the pattern are too consistent to ignore.

The Five Pathways of Concern

At the core of the paper is Figure 1, which lays out five cancer-driving pathways that the SARS-CoV-2 spike protein — delivered via synthetic mRNA — may disrupt:



  1. Metabolic Reprogramming: Cancer cells shift into the “Warburg effect,” using inefficient glycolysis even in oxygen-rich environments. The spike protein impairs mitochondrial function, forcing this shift and favoring tumor growth.
  2. Cancer Stem Cell Propagation: Spike protein activity may fuel stem-like cancer cells that regenerate tumors, evade treatment, and spread to new sites.
  3. Apoptosis Resistance: By interfering with the p53 tumor suppressor pathway, the spike protein can allow abnormal cells to evade programmed cell death.
  4. Angiogenesis & Metastatic Potential: Spike-driven inflammation and VEGF upregulation promote new blood vessel growth to feed tumors and help them spread.
  5. Immune Dysfunction & Tumor Microenvironment Disruption: Vaccine-induced IgG4 antibodies, lymphopenia, and myeloid-derived suppressor cells can blunt the immune system’s ability to detect and destroy cancer cells.

“Clinicians need to be aware of this fact. We may be facing a tsunami of uncontrolled cancer due to the vaccine.” — Dr. Paul Marik

The study authors note that while any one of these processes can drive cancer progression, the real danger may be in their combination — a “multi-hit” effect that overwhelms the body’s defenses.

More Red Flags Pointing to Turbo Cancer

Beyond the five primary mechanisms, Marik and Hope point to other possible contributors to post-vaccine cancer risk:
  • Epstein-Barr virus reactivation and other herpesviruses that can drive cancer progression.
  • SV40 DNA sequences detected in vaccine vials, historically linked to oncogenic potential.
  • N1-methyl-pseudouridine in mRNA, which in lab models has promoted tumor growth.
  • Lipid nanoparticle accumulation in tumors, potentially altering their microenvironment.
  • Retrotransposon activation and possible reverse transcription of vaccine RNA into host DNA.
  • Codon optimization effects on microRNA regulation, influencing gene expression in ways that may favor cancer.

“Given the consistent temporal association and biological plausibility, it is imperative to investigate these phenomena with objectivity and scientific rigor.” — Dr. Paul Marik & Dr. Justus Hope, Journal of Independent Medicine

While some of these remain speculative, the authors argue they are credible enough to warrant immediate research.

Why This Study Matters

Most mainstream journals, Dr. Marik notes, “would probably almost exclusively reject this paper because it challenges the orthodoxy.” That is why the Journal of Independent Medicine — an independent, open-access platform — is so vital. It allows rigorous but controversial research to reach clinicians, scientists, and the public without being buried by censorship or institutional bias.

You can read the full study here: COVID-19 mRNA-Induced ‘Turbo Cancers’

2025 Studies and Updates: mRNA COVID Vaccine and Cancer?

Landmark study reveals COVID-19 “vaccines” severely disrupt the expression of thousands of genes—triggering mitochondrial failure, immune reprogramming, and oncogenic activation

In a groundbreaking landmark study (July 2025) titled “Synthetic mRNA Vaccines and Transcriptomic Dysregulation: Evidence from New-Onset Adverse Events and Cancers Post-Vaccination”—scientists discovered that COVID-19 mRNA injections can trigger profound, long-lasting genetic dysregulation in individuals who develop new-onset adverse events or cancer following vaccination.

The study was conducted by scientists from Neo7Bioscience (Dr. John Catanzaro, Dr. Natalia von Ranke, Dr. Wei Zhang, Dr. Philipp Anokin), the University of North Texas (Dr. Danyang Shao, Dr. Ahmad Bereimipour, Minh Vu), the McCullough Foundation (Dr. Peter McCullough and Nicolas Hulscher) and Medicinal Genomics (Kevin McKernan).

Using high-resolution RNA sequencing of blood samples and differential gene expression analysis, we found that COVID-19 “vaccines” severely disrupted the expression of thousands of genes—inducing mitochondrial failure, immune system reprogramming, and oncogenic activation that persisted for months to years after injection.

These findings strongly suggest:
  • mRNA vaccines can induce gene expression profiles consistent with tumor formation and chronic disease
  • mRNA-vaccinated individuals may be at heightened risk of cancer, immune dysfunction, and inflammatory disorders
  • The synthetic mRNA and long-lasting spike protein appear to create sustained cellular stress that disrupts normal genetic regulation
  • Signatures suggest potential reverse transcription of vaccine mRNA and persistence of plasmid DNA—raising concern for long-term transcriptional interference or possible genomic integration.

mRNA Shots Induce Cancer-Linked Bone Marrow Reprogramming Within Weeks: 2025 Study

The study titled, Metabolomic Profiling of Leukemic Hematopoiesis: Effects of BNT162b2 mRNA COVID-19 Vaccine Administration, was published in Current Molecular Medicine in June 2025.

Researchers analyzed bone marrow samples from three groups using untargeted metabolomics, a powerful technique that detects thousands of small molecules reflecting real-time cellular activity:
  1. Vaccinated leukemia patients (n=7) — all of whom developed leukemia within 15 to 63 days after receiving Pfizer’s BNT162b2 COVID-19 mRNA injection
  2. Unvaccinated leukemia patients with no history of COVID-19 (n=2)
  3. Healthy, unvaccinated individuals (n=7)
Here’s what they found:

As expected, the metabolic profiles of both leukemia groups were markedly different from healthy controls—showing classic cancer-linked changes like:
  • ↑ Glycolysis (sugar breakdown)
  • ↑ Pentose phosphate pathway (nucleotide synthesis and redox balance)
  • Altered tryptophan metabolism, known to create an immunosuppressive tumor environment
  • Disrupted heme metabolism, involved in red blood cell formation and oxidative stress
However, the vaccinated leukemia group showed additional, distinct metabolic alterations that were not present in unvaccinated leukemia patients, including:
  • ↑ Tetrahydrofolic acid — vital for DNA synthesis, repair, and methylation. Uniquely elevated in vaccinated leukemia patients, possibly reflecting folate cycle modulation or compensatory changes in nucleotide metabolism.
  • ↑ Phosphorylcholine — a marker of altered membrane metabolism, linked to tumor progression, lipid signaling, and immune activation. Elevated only in vaccinated leukemia patients, contrasting with a decrease in unvaccinated leukemia cases.
  • ↑ N-Formyl-L-glutamic acid / N-Acetyl-L-aspartic acid — involved in amino acid and mitochondrial metabolism. Significantly elevated in vaccinated leukemia patients, not seen in unvaccinated leukemia individuals.
  • ↑ Delta 8.14-Sterol — a sterol lipid involved in membrane structure and cellular signaling. Increased only in the vaccinated leukemia group, potentially indicating vaccine-induced disruption of lipid regulation.
All seven vaccinated leukemia patients developed cancer within two months of mRNA injection.

Turbo cancers and repurposed drugs: Dr William Makis and Dr John Campbell (YouTube 2025)

 

Turbo Cancers on the Rise: Yale experts

Dr. Harvey Risch first reported in September 2023 that Clinicians at Yale Medical School were seeing some new cancer situations in adults as young as 25, with no family history of developing colorectal cancer, suddenly developing highly aggressive forms of the disease. So aggressive that between diagnosis and first treatment, the cancers have grown dramatically (1). This phenomenon has rapidly accelerated since the Pandemic.

These ‘turbo cancers’ do not conform to the normal behaviour of cancers, not only are they more aggressive, but there seem to be more genetic issues in these cancers.

Risch is Professor Emeritus of Epidemiology in the Department of Epidemiology and Public Health at the Yale School of Public Health and Yale School of Medicine.

 

In 2022 there was a report in Nature (2) from researchers at Harvard, amongst others referring to increases in young cancer, often described as Early Onset Cancer. Yale Researchers believe early onset cancer has gone turbo since the pandemic.

 

The CEO of the American Cancer Society described the report as “a call to arms.”

Doctor Jeremy Kortmansky and Doctor Mariya Rozenblit of Yale Medicine have observed that younger adults tend to have more aggressive-appearing cancers compared to older adults. And, so far, this difference is seen in various cancer types, including colorectal, gastric and oesophageal cancers and breast cancer. In fact, Yale Cancer Center has now developed an ‘Early Onset Cancer Program’ to focus on patients with these aggressive cancers and diagnosed between the ages of 18-49. They have done this in partnership with the Smilow Cancer Hospital, a leading comprehensive cancer center in Connecticut, affiliated with the Yale Cancer Center.

 

Dr Veda Giri is the newly appointed director in charge of Yale Cancer Center and Smillow’s Early Onset Program. When Dr. Giri surveyed Smilow’s patient records from the last two years, she discovered approximately 1,300 cases of early onset breast cancer, about 600 cases of early onset gastrointestinal cancers, and close to another thousand cases across other cancer types. These new figures came as a shock. “It’s a real issue that has to be prioritized,” Giri stated.

 

But it’s not just the aggression of these cancers; the genetic issues mean that drugs may not currently exist to treat these cancers. Then younger patients may also have young families, may have more financial issues and may worry more about fertility.

Studies and Case Reports of Cancer Following COVID-19 Vaccination?

Studies and case reports of various cancers following mRNA vaccination are helping experts understand the potential mechanisms that may be allowing these cancers to proliferate.

In a 2023 Belgian study published in Frontiers Oncology, researchers presented the first case of malignant lymphoma in mice. Malignant lymphoma is a rare adverse event reported following mRNA COVID-19 vaccination.

Two days after receiving a booster dose of Pfizer’s COVID-19 vaccine, one of 14 mice suffered spontaneous death. Upon examination, the 14-week-old mouse had abnormally large organs and cancerous lymphoma in the liver, kidneys, spleen, heart, and lungs. Although showing direct causality is complex, the authors said their findings add to “previous clinical reports on malignant lymphoma development following novel mRNA COVID-19 vaccination.”

In a January 2023 paper in Medicina, researchers presented the case of a 66-year-old man who developed swollen lymph nodes 10 days after receiving his third dose of Pfizer. After further testing, the patient was diagnosed with stage 2 non-Hodgkin lymphoma (NHL). A literature review found eight additional cases of NHL that developed shortly after COVID-19 vaccination. Five lymphoma cases occurred after vaccination with Pfizer, one case after vaccination with AstraZeneca, one after the Johnson & Johnson shot, and one after vaccination with Moderna.

In an August 2022 Letter to the Editor in the Journal of the European Academy of Dermatology & Venereology, physicians described two patients diagnosed with diffuse large B-cell lymphoma that developed from swollen lymph nodes following vaccination with Pfizer’s COVID-19 vaccine.

The study’s authors found that diffuse large B-cell lymphoma “may rapidly grow” after vaccination with Pfizer’s COVID-19 vaccine and urged dermatologists to pay attention to swollen lymph nodes or masses near the injection site.

Swollen lymph nodes, or lymphadenopathy, is considered a common side effect of COVID-19 vaccination, more often observed following immunization with novel COVID-19 mRNA vaccines than other vaccines.

Lymphadenopathy is also an acknowledged “non-serious” adverse event of COVID-19 vaccination listed in the U.S. Food and Drug Administration’s (FDA) fact sheets for health care providers for both Moderna and Pfizer’s monovalent and bivalent vaccines. However, pharmaceutical companies and U.S. regulatory agencies have not assessed whether there’s a link between vaccine-related lymphadenopathy and cancer.

Urgent Need to Determine Underlying Causes of Turbo Cancers - Dr.William Makis 

In a September 22, 2023, Highwire interview (video below), Canadian oncologist and cancer researcher Dr. William Makis discussed the alarming rise in post-jab "turbo cancers," a term coined to describe incredibly rapid-growing cancers in people who have received one or more COVID jabs.
 

The exact mechanism giving rise to turbo cancers is unknown, and it’s unclear whether one or multiple mechanisms are responsible for these cancers, Dr. William Makis, an oncologist, cancer researcher, and nuclear medicine radiologist, told The Epoch Times in an email.

Dr. Makis provided the following several possible hypotheses for how mRNA COVID-19 vaccines could cause turbo cancers:

1. The current COVID-19 mRNA vaccines contain pseudouridine-modified mRNA, which attenuates or alters the activity of key proteins in the innate immune system, impairing cancer surveillance.

When activated, these key proteins, called toll-like receptors, can prevent tumors from forming and growing.

2. Vaccination alters T-cell signaling that induces profound impairment in type 1 interferon and cancer surveillance.

T-cells, a type of white blood cell, help the body’s immune system prevent cancer. Studies show that getting multiple shots increases the level of a particular antibody called IgG4, causing T-cell and interferon suppression, leading to an inability to keep cancer in check, Dr. Cole told The Epoch Times.

“Everyone gets atypical cells in their body every day, and having a surveillance system is important, but when the surveillance system is shut off, that allows these cells to go haywire. How long it stays suppressed, nobody knows, and these are the studies NIH (the National Institutes of Health) should have been doing,” said Dr. Cole.

3. The shift of the antibody IgG4 caused by repeated mRNA vaccination could create a tolerance for spike protein and impair the production of the antibodies IgG1 and IgG3 and cancer surveillance.

4. The spike protein produced by the body after COVID-19 mRNA vaccination may interfere with important tumor suppressor proteins—P53, BRCA 1, and two tumor suppressor genes.

5. The spike protein may interfere with DNA repair mechanisms.

6. The RNA from the COVID-19 vaccines may be reverse-transcribed and integrated into the human genome.

7. Pfizer and Moderna vials found to be contaminated with plasmid DNA containing SARS-CoV-2 spike protein may integrate into the human genome.

8. The presence of the simian virus 40 (SV40) in DNA discovered in Pfizer mRNA vaccine vials may lead to cancers—most notably, non-Hodgkin lymphoma and other lymphomas—as it did with SV40-contaminated polio vaccines.

9. mRNA-based vaccines may be triggering the release of oncogenes—oncomiRs or microRNAs, which can enhance or inhibit cancer development and participate in cancer biological processes, such as proliferation, invasion metastasis, angiogenesis, chemoresistance, and immune escape.

“I believe there is an urgent need to determine the underlying mechanisms of turbo cancers because, at this time, oncologists have nothing to offer patients who have developed a turbo cancer, and conventional cancer treatments offer minimal or no benefit,” Dr. Makis told The Epoch Times.

Mr. David Wiseman, a research scientist in pharmacy, pharmacology, and experimental pathology, told The Epoch Times in an email that neither Comirnaty—Pfizer’s fully approved version of its COVID-19 vaccine—nor Spikevax by Moderna has been evaluated for its potential to cause cancer.

On March 30, 2023, Mr. Wiseman and four other experts submitted a 27-page document to the National Academies Committee, an ad hoc committee tasked with reviewing relevant adverse events associated with COVID-19 vaccines.

Using the Vaccine Adverse Event Reporting System (VAERS)—a database co-managed by the U.S. Centers for Disease Control and Prevention (CDC) and FDA used for reporting vaccine adverse events—Mr. Wiseman and his coauthors found an excess of cancer signals for COVID-19 vaccines from Dec. 14, 2020, to July 24, 2023, compared to all other vaccines for all years beginning in 1990.

A safety signal indicates a condition may be linked to a vaccine but requires further analysis to confirm an association.

The findings complemented the CDC’s Proportional Reporting Ratio (PRR) analyses obtained through a Freedom of Information Act (FOIA) request that assessed adverse events reported from Dec. 14, 2020, to July 29, 2022.

A PRR compares reports of specific adverse events experienced after receiving Moderna or Pfizer’s COVID-19 vaccine to those following vaccination with any other vaccine or all non-COVID-19 vaccines. The CDC’s PRR report detected cancer signals for colon cancer, metastatic breast cancer, metastasis to the liver, bones, central nervous system, lymph nodes, breast masses, chronic lymphocytic leukemia, B-cell lymphoma, and follicular lymphoma.

Mr. Wiseman said it’s clear from the FOIA documents that the CDC is aware of cancer reports and isn’t being forthcoming.

“Government agencies knew there were going to be cancers with these shots, and they were trying to cover it up, but the data is trickling out,” Dr. Cole told The Epoch Times, referring to 490 pages of communications obtained from the NIH through a FOIA request.

The CDC is supposed to report on morbidity and mortality—and when a pathologist diagnoses anything, he or she uses a diagnosis code, and it goes to the federal basis that’s reported to federal tracking agencies, Dr. Cole explained.

“All these data subsets should be easy to find if agencies would report what they have,” he said. “We could see statistical changes in diagnosis in the past two and a half years since shots were rolled out. The question is, why are other governments around the world not doing this?”

Case Reports of Turbo Cancer?

Case 1: 34 year old female, a star of "The Bachelorette" was diagnosed with Stage 3 Breast Cancer.

Dr William Makis shared on X/Twitter in March 2025:

TURBO CANCER - 34 year old Katie Thurston, a star of "The Bachelorette" was diagnosed with Stage 3 Breast Cancer. 
She had COVID-19 Vaccines in 2021 and promoted them. Pfizer and Moderna COVID-19 mRNA Vaccines cause Turbo Cancer and Breast cancer is the 2nd most common Turbo Cancer. 
Millions of mRNA Vaccinated women face an elevated breast cancer risk as a result of the jabs, for the rest of their lives. 
Stage 3 Breast cancer in a 34 year old woman? This used to be rare. Sadly, not anymore!
Case 2: 27 year old College Athlete with Stage 4 Colon Cancer to liver

Dr William Makis shared on X/Twitter in March 2025:

IVERMECTIN and FENBENDAZOLE Testimonial - 27 year old College Athlete with Stage 4 Colon Cancer to liver after COVID-19 mRNA Vaccines, has excellent response! I believe we have a 27 year old with Turbo Cancer 27 year old College Athlete developed Stage 4 Colon Cancer after COVID-19 mRNA Vaccines in 2021 (possible Turbo Cancer) Primary tumor was removed but patient has liver metastases.
 
We started on Feb.10, 2025: 
  • Ivermectin 1.5mg/kg/day
  • Fenbendazole 1500mg/day
  • Oncologist started chemo 
RESULTS: (after 1 month)
  • CEA 748 to 47.2 (94% drop)
  • CA125 81 to 9 (89% drop)
  • Liver metastasis size: 2.6cm to 2.2cm
“I truly believe your protocol is working wonders for me…” 

The synergy between chemo + Ivermectin + Fenbendazole can yield stunning results that are shocking Oncologists around the world.
 

Case 3: 26-year-old with stomach pain diagnosed with stage 4 colon cancer

A 26-year-old with stomach pain diagnosed with stage 4 colon cancer. (Business Insider)


Case 4: 39-year-old woman diagnosed with “vaccination-associated reactive lymphadenopathy” following vaccination (JAMA)
A year after the vaccine rollout, researchers published a case report in the Journal of the American Medical Association (JAMA) of a healthy 39-year-old woman diagnosed with “vaccination-associated reactive lymphadenopathy” following vaccination with Pfizer’s vaccine. Six months later, she was diagnosed with invasive breast cancer in her right breast—the same side of the body where she received her vaccination and experienced swollen lymph nodes.

Got the Jab? Take Action to Safeguard Your Health

If you developed symptoms you didn’t have before your shot, I would encourage you to seek out expert help. In light of the frequency of turbo cancers, postmenopausal women with breakthrough bleeding after their COVID jab would probably be wise to get evaluated to rule out endometrial cancer.

At present, the Independent Medical Alliance (previously Front Line COVID-19 Critical Care Alliance - FLCCC) seems to have one of the best treatment protocols for post-jab injuries. It’s called I-RECOVER protocol.


 


Sources and References

 

https://www.canceractive.com/article/yale-experts%20see%20rise%20in%20younger%20turbo%20cancer.

1. The rise of turbo cancer in young people; https://www.theepochtimes.com/epochtv/dr-harvey-risch-rise-in-aggressive-turbo-cancers-and-especially-among-younger-people-atlnow-5489582.
2. Is early-onset cancer an emerging global epidemic? Current evidence and future implications; Ugai, T., Sasamoto, N., Lee, HY. et al. Nat Rev Clin Oncol 19, 656–673 (2022). https://doi.org/10.1038/s41571-022-00672-8.

3. Professor sees vaccines causing cancer - https://www.canceractive.com/article/top-professor%20sees%20vaccines%20causing%20cancer.


5. Turbo Cancers and Alternative Cancer Treatments (A Midwestern Doctor)

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