Dr Peter McCullough: Nasal Spray and Mouth Gargle to stop COVID?

By Editorial Team -

Dr. Peter McCullough has impeccable academic credentials. He's an internist, cardiologist, epidemiologist, a full professor of medicine at Texas A&M College of Medicine in Dallas. He also has a master's degree in public health and is known for being one of the top five most-published medical researchers in the United States and is the editor of two medical journals.

McCullough Protocol
McCullough et al. Reviews in Cardiovascular Medicine, 2020

McCullough Protocol 2022
McCullough Protocol 2022

Dilute Povidone Iodine or Betadine (a 1% solution) gargling and as a nasal spray on a regular basis twice a day for prevention and then if you have been exposed or are in early stages use at least 4 or potentially 6 times a day. You can also use dilute hydrogen peroxide or dilute sodium hypo chloride or even Scope or Listerine – obviously do not swallow and spit out.


In a January 2025 post on X.com, Dr Peter McCullough also suggested "Twice Daily Nasal Sprays and Gargles Best Prevention During Cold and Flu Season".

According to Dr Peter McCullough (source):

I have interviewed multiple individuals who have had zero colds in 2024—the common factor is the daily use of nasal sprays and gargles. I have learned the brand you choose is less important than committing to twice daily use—like flossing and brushing your teeth. Here are the two pairs I most commonly recommend.
In the September 2021 interview (below) with Peter Breggin MD, author of Talking Back to Prozac, Dr. Peter McCullough discusses the routine use of diluted (1%) Povidone Iodine mouth wash in the dental office as an excellent preventive measure for COVID-19. 

10% Povidone Iodine is available OTC (Over the Counter) without a prescription at any drug store for a few dollars. 

Note: This 10% Povidone Iodine must be diluted by one tenth, to 1% strength before use as a mouth wash, otherwise it is too strong and irritating. Dilute by adding 2 tablespoons (30 ml) of the 10% Povidone Iodine into a full glass of water (250-300 ml). This will make the product diluted enough to use as a mouth rinse, or gargle, (approximately 1.0 to 1.2 %)

2 tablespoons = 30ml povidone iodine
1 glass water = 250-300 ml

Dr. McCullough recommends routine use of this mouthwash on a daily basis, and especially after contact with large indoor groups.

Dr Peter Breggin Interview with Dr Peter McCullough on Brighteon discussing COVID, vaccines, early treatment, prevention with Povidone Iodine mouth wash etc:

  

According to a mainstream media channel, "There appears to be no reliable data that suggests that povidone-iodine can help prevent COVID-19 or its spread...".

It's important to note that the scientific community relies on evidence-based research to inform medical recommendations and guidelines. If you come across information about a treatment or approach that is not widely accepted or that lacks strong scientific evidence, it's a good idea to do your own research and consult with a healthcare professional before making any decisions.

We have included the scientific evidence together with the sources and references below and we leave it up to you, the reader, to decide. 

Povidone iodine (PVP-I) is an antiseptic that has been used for over 150 years. The antiseptic has immediate virucidal effects against COVID-19 virus. 

There are more than 20 published studies supporting povidone-iodine for COVID-19. You can check out the list at c19pvpi.com (constantly updated).

In this December 4th, 2021 interview with Rebel News, Peter McCullough MD discusses what is known about the Omicron variant, and the use of Povidone Iodine Mouthwash, Nasal Wash and gargle for prevention of Covid-19. Dr. McCullough cites the Choudhury study in which 600 Covid infected patients were randomized to 1% povidone iodine, or saline placebo mouthwash and gargle. Patients were followed with PCR testing for viral load. Dr. Choudhury writes:

The group of patients used 1% PVP-I [One per cent Povidione Iodine Solution] have shown tremendously reduced mortality, morbidity and hospital as well as financial burden in this covid situation.

A study by Avinash Bidra found complete inactivation of the virus after 15 seconds of gargling with a 1% Povidone Iodine Solution. According to the authors, Povidone Iodine (1%) solution is “rapidly virucidal” at all dilutions tested.


Saline Alternative

You can also do nasal rinses and gargle with saline instead of povidone-iodine. According to research (Double blind randomized controlled trial of saline solution gargling and nasal rinsing in COVID infection) presented at the annual meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in early November 2023, gargling and rinsing your nasal passages with a simple saline solution can ease the respiratory symptoms of COVID-19 and reduce your risk of hospitalization.

The results have not yet been published in a peer-reviewed medical journal. As reported in an ACAAI press release,1 both high- and low-dose saline regimens, consisting of gargling and nasal rinsing four times a day for 14 days, were associated with significantly lower hospitalization rates for COVID-19 infections compared to the reference population.


Online Shopping Guide:
mouthwash for COVID-19
Best Mouthwashes for Coronavirus

Related:


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