Nasal Irrigation and COVID 2022

There is a study proposing a simple prevention/treatment method that can be made/applied in just about any country, regardless of how poor and remote it is. Namely, a simple solution of salt in water, such that the concentration of salt is about 1.5% (e.g. commonly known as “hypertonic”) in the solution, had a 100% effectiveness of stopping SARS-CoV-2 replication.  

This effectiveness actually exceeds the results (90% inhibition) demonstrated by the study on low-dose vitamin E mentioned above. As the study says, this simple hypertonic saline solution can be administered as a nasal spray as a prophylactic method, or for treating early stages of the infection. For already established or more severe cases affecting the lungs, a nebulizer may have to be used so that the salt vapors can reach the lower regions of the respiratory tract. 

The mechanism of action for the anti-viral effects of the saline is remarkably simple – i.e. the extra salt from the solution accumulates into the cells, which forces them to expend ATP in order to re-balance the electrolyte gradient, and this limits the amount of ATP available for viral replication. Since virtually all viruses, including SARS-CoV-2, depend for their survival on being able to hijack ATP for their own replication this study suggests hypertonic saline may be a universally applicable antiviral treatment.

Saline Nasal Spray COVID-19 Studies and Updates: 

Aug 17, 2021: Rapid initiation of nasal saline irrigation: hospitalizations in COVID-19 patients randomized to alkalinization or povidone-iodine compared to a national dataset

Patients who initiated isotonic saline nasal irrigation after a positive COVID-19 PCR test were 19 times less likely to be hospitalized than the national rate. 

July 2, 2021: Doctors at Pune's Deenanath Hospital claim traditional jalneti is helping them steer clear of COVID-19

Jalneti is a yoga technique, in which sterilised and lukewarm isotonic salt water is poured into one nostril so that it leaves through the other.

“The COVID-19 virus gets lodged in the nostril. It has been found that a person tests positive on the fourth day after this happens. So, the virus seems to establish a colony during these four days. We are trying to wash out the virus and reduce the viral load on a daily basis via this method."

March 2021: COULD A SIMPLE SALINE NASAL IRRIGATION AND GARGLING SOLUTION STOPS COVID?

Feb 2, 2021 - Indian prospective controlled study (n=251) of saline nasal spray and gargle shows positive impact on PCR negativity and lung involvement. Many studies with different products now point to the very beneficial impact of that cheap, simple procedure.

Uday Chatterjee, Ajay Chakraborty, Sishir Naskar, Bibhuti Saha, Bhaswati Bandyapadhyay, Subhasis Shee.

Efficacy of normal saline nasal spray and gargle on SARS-CoV-2 for prevention of COVID-19 pneumonia.

https://www.researchsquare.com/article/rs-153598/v1

Nozin Nasal Sanitizer - Available on Amazon

Iodine nasal rinse recipe COVID | How to make povidone-iodine nasal spray

To make 1% povidone iodine nasal spray from 10% povidone iodine solution, it must be diluted first. 10% Povidone Iodine is available OTC (Over the Counter) without a prescription at any drug store for a few dollars. Here is the link: Povidone 10% Iodine on Amazon.

This 10% Povidone Iodine must be diluted by one tenth, to 1% strength before use as a nasal irrigation, otherwise it is too strong and irritating. You should have someone double check your work if you're doing your own math or triple check your work because higher concentrations can cause damage to the nasal tissue.

Dilute by adding 2 tablespoons (30 ml) of the 10% Povidone Iodine into a full glass of water (300 ml). This will make the product diluted enough to use as a mouth rinse or nasal spray, (approximately 1.0%)

Note:
2 tablespoons = 30ml povidone iodine
1 glass water = 300 ml

Bangladesh nasal rinse COVID

Dr. Iqbal Mahmud Choudhury conducted a protocol in Bangladesh that used a povidone-iodine rinse in the nose, mouth, and eyes to kill the virus. Dr. Choudhury writes:

The group of patients used 1% PVP-I [One per cent Povidone Iodine Solution] have shown tremendously reduced mortality, morbidity and hospital as well as financial burden in this covid situation.