New COVID-19 Variant NB.1.8.1 (Nimbus): Symptoms (Razor Blade Throat), Spread, and Impact in 2025

Overview A new COVID-19 variant, identified as NB.1.8.1, has recently emerged and is drawing international attention due to its increasing prevalence, particularly in China, and its detection in the United States and other countries. 1. Emergence and Spread of NB.1.8.1 Origin and Detection: NB.1.8.1 was first identified as a significant driver of rising COVID-19 cases in China. The U.S. Centers for Disease Control and Prevention (CDC) confirmed its presence in the United States, though as of late May 2025, fewer than 20 cases had been reported domestically. Global Spread: The World Health Organization (WHO) and multiple health authorities have noted that NB.1.8.1 is now spreading worldwide, with cases reported in several countries. Its rapid dissemination has raised concerns about potential increases in COVID-19 cases in various regions. 2. Variant Characteristics Genetic Profile: NB.1.8.1 is a subvariant of the Omicron lineage, featuring several mutations in the spike protein. These m...