Anti Spike Protein Effect of Ivermectin - Peter McCullough

The past three years have generated millions of case vignettes of patients with COVID-19 respiratory illness. The most dramatic cases include critically ill inpatients with severe hypoxemia despite maximum respiratory support. By far, the most notable cases of survival have occurred with the administration of ivermectin. 

Former NIH researcher David Scheim, PhD, early in the pandemic proposed that SARS-CoV-2 Spike protein was acting like a grappling hook pulling together circulating red blood cells (RBSc) into long chains and clumps in a process called hemagglutination (HA). This explained why the red blood cells could not carry oxygen normally and was congruent with the finding of micro blood clots in the lungs. Recently, Boschi et al have provided additional support for this mechanism (source).

According to the authors:

“Ivermectin blocked HA when added to RBCs prior to spike protein and reversed HA when added afterwards.”

In another spectacular publication, Stone et al, describes the prompt improvement of oxygenation in patients with ivermectin (source).


The published oxygenation curves from multiple studies clearly show this physiological effect of ivermectin occurs so rapidly, it must be explained by a direct anti-Spike protein effect of ivermectin. An anonymous video of a critically ill man demonstrates the very effect that Scheim, Stone, Hazan, and Babalola have described in the Figure above. So for the next critically ill patient with COVID-19, if the opportunity presents itself, push for the administration of ivermectin. This is the only published therapy for COVID-19 that improves oxygen saturation while the patient mounts a recovery. As in this man, it may be the critical factor for a turnaround and a chance to walk out of the hospital.


About the Authors: 

Dr. Peter McCullough is a practicing internist, cardiologist, epidemiologist managing the cardiovascular complications of both the viral infection and the injuries developing after the COVID-19 vaccine in Dallas TX, USA. He has dozens of peer-reviewed publications on the infection, multiple US and State Senate testimonies, and has commented extensively on the medical response to the COVID-19 crisis in TheHill, America Out Loud, NewsMax, and on FOX NEWS Channel.

John Leake studied history and philosophy with Roger Scruton at Boston University. He then went to Vienna, Austria on a graduate school scholarship and ended up living in the city for over a decade, working as a freelance writer and translator. He is a true crime writer with a lifelong interest in medical history and forensic medicine.

Reposted and adapted from the author’s Substack.

Views expressed in this article are the opinions of the authors.

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