Immune Systems Advisor

Abstract Background: Persistent symptoms following SARS-CoV-2 infection, commonly referred to as Long COVID, affect a significant subset of patients. Spike protein persistence, immune dysfunction, and microvascular pathology have been proposed as contributing mechanisms. Objective: To review current evidence regarding spike protein persistence, immune dysregulation, microclot formation, and systemic dysfunction in Long COVID, and to summarize evidence-informed recovery strategies. Methods: A narrative review of peer-reviewed studies and public health guidance was conducted, focusing on immunology, vascular pathology, and persistent viral antigen detection in post-acute COVID-19 patients. Sources include Nature , Cell , Clinical Infectious Diseases , and The Lancet . Results: Spike protein or viral RNA may persist in some individuals for months post-infection. Persistent immune activation, microclots, endothelial dysfunction, mitochondrial impairment, and dysautonomia are documented...

More than four years after COVID-19 first appeared, many people still suffer from long-lasting symptoms after getting infected. This ongoing condition was often called 'Long COVID'. It means symptoms stick around for three months or more after the infection or after exposure to certain COVID-19 vaccines that use mRNA technology. In late 2023, some researchers introduced a new name, "SPIKEOPATHY," to explain that a protein called the Spike protein—found in both the virus and mRNA vaccines—plays a big role in causing these long-term problems. Because of this, the term Post-Spike Syndrome (PSS) is suggested as a clearer name for this condition. What is Post-Spike Syndrome? PSS can affect many parts of the body and cause serious, long-lasting health problems. Scientists are learning more about how the Spike protein causes these issues. The tiny particles from mRNA vaccines can travel through the body, not just stay where the shot was given. Both these particles and the Sp...

Can you remove spike proteins from your body? Dr. Paul Marik and Dr. Pierre Kory are pleased to introduce the I-RECOVER: Post-Vaccine Treatment protocol, designed to help people who have experienced adverse symptoms after a COVID vaccine. Kory and Marik are both part of the FLCCC*, which was founded in 2020 to share early treatment protocols for COVID-19. Kory is an ICU specialist, triple board certified in internal medicine, critical care and pulmonary medicine. He now runs a private tele-health practice specializing in the treatment of COVID-19, so-called "long-COVID" and post-vaccine syndrome. *The FLCCC Alliance is now the  Independent Medical Alliance Note that there are significant overlaps between the symptoms and features of long COVID/long-hauler syndrome and post-vaccine syndrome. However, a number of clinical features appear to be characteristic of post-vaccine syndrome; most notably, severe neurological symptoms appear to be more common following vaccination. To c...