Ivermectin and Fenbendazole for Turbo Cancer (2024)
Preclinical studies show that both ivermectin and fenbendazole exhibit cytotoxic effects against cancer cells. The two drugs also inhibit the growth and spread of cancerous tumors.
"The mechanisms underlying these effects appear to involve disruption of critical cellular processes, leading to cancer cell death," wrote Sid Belzberg in a paper.
Both ivermectin and fenbendazole are off-patent drugs, meaning their original intended use as licensed has expired and they have become generics. This allows for many different generic drug manufacturers, including a slew of them across India, to produce them cheaply and abundantly.
United States regulators make it hard to access them without a prescription – unless you purchase the versions available for pets – but they are out there. And when combined with other anti-cancer vitamins and minerals they show incredible promise in cancer prevention and mitigation.
You will be hard-pressed to find much helpful information about these two drugs in the mainstream, though. Because they are off-patent, ivermectin and fenbendazole bring in minimal profits, which means pharmaceutical companies are not interested in promoting them or touting their benefits.
Belzberg makes the case for ivermectin and fenbendazole to be compounded with other complementary substances to create a synergistic anti-cancer concoction that is safe and effective for widespread use.
"Despite these challenges, the repurposing of these compounds carries potential advantages that justify further exploration," Belzberg wrote. "Since the safety and pharmacokinetic profiles of these substances are well-known, their development as anticancer agents could be faster and less expensive than for new drugs."
"Furthermore, the successful repurposing of these compounds could provide a cost-effective way to expand anticancer treatments, possibly improving patient outcomes while reducing healthcare costs."
Ivermectin Resources
Recently, we have seen tremendous demand for some sort of initial guidance “WHERE TO START” with High Dose Ivermectin for CANCER.2024 - NEW STUDIES
2024 Baghli et al - Targeting the Mitochondrial-Stem Cell Connection in Cancer Treatment: A Hybrid Orthomolecular Protocol(2024 Man-Yuan Li et al) - Ivermectin induces non-protective autophagy by downregulating PAK1 and apoptosis in lung adenocarcinoma cells
(2024 Kaur et al) - Ivermectin: A Multifaceted drug with a potential beyond anti-parasitic therapy
(2024 Xing Hu et al) - Ivermectin as a potential therapeutic strategy for glioma
(2024 Yang Song et al) - Gene signatures to therapeutics: Assessing the potential of ivermectin against t(4;14) multiple myeloma
(2024 Goldfarb et al) - Lipid-Restricted Culture Media Reveal Unexpected Cancer Cell Sensitivities
(2024 Newell et al) - Therapeutic targeting of nuclear export and import receptors in cancer and their potential in combination chemotherapy
Oct. 2, 2023 - IVERMECTIN and CANCER, it has at least 15 anti-cancer mechanisms of action. Can Ivermectin Treat COVID-19 mRNA Vaccine Induced Turbo Cancers? - 9 Ivermectin papers reviewed
IVERMECTIN and CANCER RESEARCH:
Top 5 COVID-19 mRNA Vaccine Induced Turbo Cancers are: Lymphoma, Glioblastoma, Breast, Colon, Lung Cancer.IVERMECTIN can help with mRNA Induced Turbo Cancer, or regular cancers.
Here are recent studies on IVERMECTIN use in certain types of cancer:
BLADDER CANCER - (2024 Fan et al) - Ivermectin Inhibits Bladder Cancer Cell Growth and Induces Oxidative Stress and DNA Damage
LUNG CANCER - (2024 Man-Yuan Li et al) - Ivermectin induces nonprotective autophagy by downregulating PAK1 and apoptosis in lung adenocarcinoma cells
GLIOMA - (2024 Xing Hu et al) - Ivermectin as a potential therapeutic strategy for glioma
MULTIPLE MYELOMA - (2024 Yang Song et al) - Gene signatures to therapeutics: Assessing the potential of ivermectin against t(4;14) multiple myeloma
OVARIAN CANCER - (2023 Jawad et al) - Ivermectin augments the anti-cancer activity of pitavastatin in ovarian cancer cells
PROSTATE CANCER - (2022 Lu et al) - Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancer
COLON CANCER - (2022, Alghamdi et al) - Efficacy of ivermectin against colon cancer induced by dimethylhydrazine in male wistar rats
PANCREATIC CANCER - (2022 Lee et al) - Ivermectin and gemcitabine combination treatment induces apoptosis of pancreatic cancer cells via mitochondrial dysfunction
MELANOMA - (2022 Zhang et al) - Drug repurposing of ivermectin abrogates neutrophil extracellular traps and prevents melanoma metastasis
CERVICAL CANCER - (2022, Qabbus et al) - Ivermectin-induced cell death of cervical cancer cells in vitro a consequence of precipitate formation in culture media
HEPATOCELLULAR CARCINOMA - (2022 Lu et al) - Ivermectin synergizes sorafenib in hepatocellular carcinoma via targeting multiple oncogenic pathways
OSTEOSARCOMA - (2022 Hu et al) - Repurposing Ivermectin to augment chemotherapy’s efficacy in osteosarcoma
GASTRIC CANCER - (2021 Rabben et al) - Computational drug repositioning and experimental validation of ivermectin in treatment of gastric cancer
LEUKEMIA - (2020, de Castro et al) - Continuous high-dose ivermectin appears to be safe in patients with acute myelogenous leukemia and could inform clinical repurposing for COVID-19 infection
ESOPHAGEAL SCC - (2020, Chen et al) - Ivermectin suppresses tumour growth and metastasis through degradation of PAK1 in oesophageal squamous cell carcinoma
CHOLANGIOCARCINOMA - (2019 Intyuod et al) - Anti-parasitic drug ivermectin exhibits potent anticancer activity against gemcitabine-resistant cholangiocarcinoma in vitro
BREAST CANCER STEM CELLS - (2018 Dominguez-Gomez et al) - Ivermectin as an inhibitor of cancer stem-like cells.
CML (CHRONIC MYELOID LEUKEMIA) - (2018 Wang et al) - Antibiotic ivermectin selectively induces apoptosis in chronic myeloid leukemia through inducing mitochondrial dysfunction and oxidative stress.
RENAL CELL CARCINOMA - (2017 Zhu et al) - Antibiotic ivermectin preferentially targets renal cancer through inducing mitochondrial dysfunction and oxidative damage
GLIOBLASTOMA - (2016 Liu et al) - Anthelmintic drug ivermectin inhibits angiogenesis, growth and survival of glioblastoma through inducing mitochondrial dysfunction and oxidative stress.
IVERMECTIN ACCESS
I recently wrote about how a doctor in Saskatchewan was just given a $44,800 penalty by the College of Physicians and Surgeons for prescribing Ivermectin to a few patients during 2020-2022. These College bureaucrats are engaging in crimes.
The Ontario College of Physicians even had an Investigator go undercover and dress up as a Canadian Trucker to ensnare a young doctor prescribing Ivermectin in Ottawa in 2022 during the Trucker Convoy.
Canadians must realize that the Colleges of Physicians are private corporations, fully bought off by big pharma and run by mafia lawyers like Bryan Salte (the SK lawyer who issued the $44,800 penalty for prescribing Ivermectin) - see below:
No healthcare bureaucrat or lawyer has the right to deny anyone access to life saving medication. And if they do, they are committing a very serious crime.
Fenbendazole
Last year Dr William Makis published one of the most popular articles on Fenbendazole and Cancer Treatment ever published, which went viral internationally.10 NEW STUDIES
- (2024 Apr, Rodrigues et al) - Repurposing mebendazole against triple-negative breast cancer CNS metastasis
- (2024 Feb, Eid et al) - Investigating the Promising Anticancer Activity of Cetuximab and Fenbendazole Combination as Dual CBS and VEGFR-2 Inhibitors and Endowed with Apoptotic Potential
- (2024 Feb, Park et al) - The microtubule cytoskeleton: A validated target for the development of 2-Aryl-1H-benzo[d]imidazole derivatives as potential anticancer agents
- (2024 Jan, Matsuo et al) - Parbendazole as a promising drug for inducing differentiation of acute myeloid leukemia cells with various subtypes
- (2023, Dec, Iragavarapu-Charyulu et al) - A novel treatment to enhance survival for end stage triple negative breast cancer using repurposed veterinary anthelmintics combined with gut‑supporting/immune enhancing molecules
- (2023 Nov, Aliabadi et al) - In vitro and in vivo anticancer activity of mebendazole in colon cancer: a promising drug repositioning
- (2023 Nov, Jung et al) - Fenbendazole Exhibits Differential Anticancer Effects In Vitro and In Vivo in Models of Mouse Lymphoma
- (2023 Sep, Garg et al) - Network pharmacology and molecular docking study-based approach to explore mechanism of benzimidazole-based anthelmintics for the treatment of lung cancer
- (2023 Jun, Mukherjee et al) - Ketogenic diet as a metabolic vehicle for enhancing the therapeutic efficacy of mebendazole and devimistat in preclinical pediatric glioma
- (2023 Feb, Lee et al) - Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine
Fenbendazole vs Mebendazole: COST
Fenbendazole is not FDA approved. It’s dirt cheap.
Mebendazole is FDA approved. It’s expensive.
Albendazole is FDA approved. It’s very expensive.
PRACTICAL APPROACH TO USING FENBENDAZOLE IN CANCER TREATMENT (Disclaimer: the following is not medical advice)
There is one article I want to highlight though because it has an extremely important concept:
(2023 Jun, Mukherjee et al) - Ketogenic diet as a metabolic vehicle for enhancing the therapeutic efficacy of mebendazole and devimistat in preclinical pediatric glioma
“This study investigated the influence of nutritional ketosis on the therapeutic action of mebendazole (MBZ) and devimistat (CPI-613) against the highly invasive VM-M3 glioblastoma cells in juvenile syngeneic p20-p25 mice”
“maximum therapeutic benefit of mebendazole and CPI-613 on tumour invasion and mouse survival occurred only when the drugs were administered together with a ketogenic diet (KD)
KETOGENIC DIET IS CRUCIAL IN CANCER
Since my previous Fenbendazole article, I‘ve had 1000s of questions sent to me. Not about mechanisms of action against Cancer. But about practical use - how to use Fenbendazole or Mebendazole to treat Stage 4 Cancers, what formulations, what doses?The goal of this article (Part 2) is to answer many of those questions to the best of my ability.
EXPERIMENTAL CANCER PROTOCOLS:
You can look at fenbendazole.org for suggested dosing and dose calculator
Dr.Tom Rogers, Founder of “Performance Medicine” has similar protocols.
For anyone COVID-19 mRNA Vaccinated diagnosed with cancer (Turbo Cancer), I’d probably be looking at starting at 444 mg a day.
For particularly aggressive Turbo Cancers or bad cases, I’d even consider pushing towards 888 mg/day (444 mg twice a day) or 1000 mg/day.
Highest dosing I’ve seen is 30-50mg/kg/day for 5 days, based on the “Merck Manual”, however very few claim to have taken this dose.
Fenbendazole can elevate liver function tests, so it would be a good idea to have a family doctor monitor those
WHAT ABOUT MEBENDAZOLE?
Here are the references for this dosing schedule:
For Maximum dose of 4g/day being safe, that’s from a Phase 2 Clinical Trial for Gastrointestinal Cancer: (2021 Mansoori et al)
(2021 Chai et al) - summarizes the various studies that have looked at Mebendazole in Cancer and the doses used.
500mg-1500mg/day (Phase 1 Clinical Trial, pediatric brain tumors)
200mg/day (2011 Dobrosotskaya et al) (adrenocortical ca)
200mg/day (2014 Nygren et al) (colon ca lung and LN mets)
100mg/day (Clinical Trial, UK)
So far, several studies in the literature have used 200mg/day with some success, however given that it is safe to go up to 4g/day, when we’re dealing with aggressive mRNA Induced Turbo Cancers, 200mg/day is probably not sufficient.
Why Mebendazole over Albendazole (2021 Chai et al):
“However, because of the toxicity of albendazole, for example, neutropenia due to myelosuppression, if high doses are used for a prolonged time, mebendazole is currently more popularly used than albendazole in anti-cancer clinical trials.”
New & Improved Joe Tippens Protocol
Fenbendazole (300mg, 6 days a week) or in the case of severe turbo cancers up to 1 gram.
Ivermectin (24mg, 7 days a week) or in the case of severe turbo cancers up to 1mg/kg/day (Find a Doctor)
Bio-Available Curcumin (600mg per day, 2 pills per day 7 days a week).
Vitamin D (62.5 mcg [2500 IU] seven days a week).
Tocotrienol and Tocopherol forms (all 8) of Vitamin E (400-800mg per day, 7 days a week). A product called Gamma E by Life Extension (Amazon) or Perfect E are both great.
Removing sugar and processed foods from one’s diet is crucial during this protocol (BMJ 2023), eating a nutritious fresh whole-food diet with fruits and vegetables (BMJ 2024) and a healthy lifestyle with less stress and good quality sleep.
CBD oil (1-2 droppers full [equal to 25mg per day] under the tongue, 7 days a week)
CBD-X: The most potent full spectrum organic CBD oil, with 5,000 milligrams of activated cannabinoids and hemp compounds CBD, CBN & CBG per serving.
Conclusion
This article deals with the practical approach to using Ivermectin, Fenbendazole or Mebendazole for turbo cancer.
Everyone’s situation is different, however, it is important to arm yourself with medical knowledge that cancer doctors (Oncologists) will simply not give you, because they either don’t know it, or they won’t risk their careers to save you.
Sources for this article:
- https://www.onedaymd.com/2024/04/fenbendazole-cancer-part-2-treating.html
- https://www.2ndsmartestguyintheworld.com/p/15-minutes-with-dr-makis-episode
- https://www.2ndsmartestguyintheworld.com/p/synergistic-pairing-of-ivermectin
- June 10, 2024 - "15 minutes with Dr.Makis" - Episode 018: High Dose IVERMECTIN and CANCER
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