6 Natural Remedies for COVID-19 Prevention: An Evidence Review 2022
Do diet, supplements and exercise help with COVID-19? Any evidence? To understand the answers, please continue reading. We have covered and done a review on supplements for COVID-19 treatment. In this article, we will cover and do a review on supplements for COVID-19 'prevention' instead.
3. Nigella Sativa (Black Seed Oil)Nigella sativa (N. sativa) is a small flowering plant that grows in Southwest Asia, the Middle East, and Southern Europe (Source). This shrub produces fruit with tiny black seeds. Commonly referred to as black seed, N. sativa seeds go by many other names, such as black cumin, black caraway, nigella, fennel flower, and Roman coriander (Source).
Black seed oil is extracted from N. sativa seeds and has been used in traditional medicine for over 2,000 years due to its many therapeutic benefits.
Melatonin is a hormone produced by the pineal gland in the brain,
mainly during the night, that helps regulate circadian rhythms [Source]. Its levels decrease with aging. Most melatonin supplementation studies have evaluated its ability to control sleep and
wake cycles, promote sleep, and reduce jet lag.
The potential utility of melatonin in treating COVID patients
has not gone unnoticed, with a PubMed search combining melatonin
and COVID producing more than 50 citations.
the evidence tracker on melatonin and COVID-19 from c19melatonin.com (constantly updated).
As of April 2022, there are more than 10 published clinical studies of melatonin for treatment and prevention in COVID-19 and
the results are promising even when it's given as a late
The 3 prevention studies provide evidence that melatonin was associated with an average
improvement of 38% in decreasing the likelihood of symptomatic
and severe cases.
Safety: If you take a melatonin supplement, be
careful: Too much can cause daytime sleepiness. There is no federal RDA nor any formal advice on supplement dose
ranges. Based on an on-going Spanish study, a 2 mg daily dose protocol is being investigated for prevention
of COVID-19. Do take note that the dosage for 'prevention' and
'treatment' is different, For prevention or maintenance, a lower
dosage is normally recommended whereas a 'treatment' or
'therapeutic' dosage is normally higher.
Typical doses of 1–10 mg/day melatonin appear to be safe for
short-term use (Source). Reported side effects, which are usually minor, include
dizziness, headache, nausea, upset stomach, rash, and sleepiness.
However, some reports have linked high blood levels of melatonin
with delayed puberty and hypogonadism.
Studies have not
evaluated melatonin supplementation during pregnancy and
breastfeeding, but some research suggests that these supplements
might inhibit ovarian function (Source). Therefore, some experts recommend that women who are
pregnant or breastfeeding avoid taking melatonin.
Check out the evidence tracker on melatonin and COVID-19 from c19melatonin.com (constantly updated).
Studies have not evaluated melatonin supplementation during pregnancy and breastfeeding, but some research suggests that these supplements might inhibit ovarian function (Source). Therefore, some experts recommend that women who are pregnant or breastfeeding avoid taking melatonin.