In this breaking interview, Dr. Takuji Shirasawa from the Ochanomizu Health and Longevity Clinic describes a 60-year old Japanese man who took 4 Pfizer COVID-19 vaccines and presented with a loss of mental clarity otherwise known as “brain fog.” Shirasawa used MR angiography to demonstrate sessile bilateral arterial thrombi in the carotid bulbs. His hypothesis was that mini-blood clots may be responsible for the neurological and cognitive symptoms.
Shirasawa performed a N-of-1 trial giving the patient a complex blend of oral proteolytic and thrombolytic enzymes featuring nattokinase, bromelain, serrapeptase, and papain adding over a dozen natural ingredients given in proprietary blends from Texas based Phytomedic Labs. The patient was also administered aspirin 100 mg per day.
Serial d-dimer levels showed a spike in concentration as the blood clots were lysed and shown to resolve over serial MR angiographic scans with virtual angioscopy. As the blood clots disappeared the patient’s brain fog lifted. I can tell you as a cardiologist these images are stunning.
First-in-man reports are very important in medicine. Such reports for coronary angioplasty and stenting changed medical history. Dr. Shirasawa’s case may have a similar historical impact as the medical community is even better supported with the mechanistic rationale for McCullough Protocol Base Spike Detoxification and even more intensive protocols in the future.
Base Spike Detox According to Dr Peter McCullough (in a X/Twitter post): Base Spike Detox is what I am currently using in my practice for those who have had COVID-19 multiple times, one or more of the COVID-19 vaccines, or both and believe persistent SARS-CoV-2 Spike protein could be causing problems in their body. I have arrived, based on the emerging scientific literature (1) and my clinical observation, that three OTC products are essential as a triple base combination: Nattokinase 2000 FU (100 mg) twice a day — take on an empty stomach Bromelain 500 mg once a day — take on an empty stomach Nano/Liposomal Curcumin 500 mg twice a day — take with food How long should I take this? Dr. McCullough recommends a minimum of 3 months , with many patients requiring 6–12 months or longer. Progress can be tracked via a spike protein antibody test (available through Labcorp in m...
Immune Systems Advisor · Integrative Medicine White Paper · Open Access Authors: OneDayMD Editorial Team (synthesis and editorial adaptation) · Original protocols: Marik P, Kory P (IMA/FLCCC, 2022–2024); McCullough PA (Cureus, 2023) · Published: March 2023 · Last updated: June 2026 · DOI: n/a (educational synthesis) Evidence Tier Key: TIER 1 RCT / systematic review TIER 2 Observational / cohort TIER 3 In vitro / mechanistic TIER 4 Expert consensus / clinical observation ⚠ Medical Disclaimer — Please Read First. This article is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The protocols described involve supplements with significant anticoagulant activity. Always consult a licensed physician before starting, especially if you take blood thinners, are pregnant or breastfeeding, have a bleeding disorder, or...
Dr. McCullough explained (1) that the spike protein is an engineered, synthetic molecule roughly 1,200 amino acids long and resistant to degradation by the body’s normal proteases. He described how the protein was modified in laboratory settings (notably at the Wuhan Institute of Virology) to tightly bind to the ACE2 receptor, which is found throughout the body—in the lungs, heart, endothelium, kidneys, and brain. Because this receptor regulates angiotensin metabolism, older individuals with fewer ACE2 sites catabolize the spike less efficiently, leading to worse outcomes. Whether introduced by infection or by genetic‑code‑based vaccines, McCullough asserted, the persistent spike damages tissues directly and through chronic inflammation, micro‑clotting, and autoimmune cross‑reactivity. Spike Protein Protocol Personalizer Based on Dr. Peter McCullough's Base Spike Detox & FLCCC I-Recover Frameworks ⚠ Medical Disclaimer: This tool is...
A clinician-developed regimen of nattokinase, bromelain, and curcumin for clearing persistent SARS-CoV-2 spike protein — with dosing, safety guidance, monitoring, and full FAQ. Editorial Team | Originally published March 2023 | Last updated June 30, 2026 | Reviewed against published literature and Dr. McCullough's 2025 clinical updates ⚠️ Medical Disclaimer — Please Read First This article is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The Base Spike Detox protocol involves supplements with significant anticoagulant activity. Always consult a licensed physician before starting , especially if you are taking blood thinners, are pregnant or breastfeeding, have a bleeding disorder, or are treating a child. For a virtual consultation with a physician familiar with this protocol, vis...
Can you remove spike proteins from your body? Dr. Paul Marik and Dr. Pierre Kory are pleased to introduce the I-RECOVER: Post-Vaccine Treatment protocol, designed to help people who have experienced adverse symptoms after a COVID vaccine. Kory and Marik are both part of the FLCCC*, which was founded in 2020 to share early treatment protocols for COVID-19. Kory is an ICU specialist, triple board certified in internal medicine, critical care and pulmonary medicine. He now runs a private tele-health practice specializing in the treatment of COVID-19, so-called "long-COVID" and post-vaccine syndrome. *The FLCCC Alliance is now the Independent Medical Alliance Note that there are significant overlaps between the symptoms and features of long COVID/long-hauler syndrome and post-vaccine syndrome. However, a number of clinical features appear to be characteristic of post-vaccine syndrome; most notably, severe neurological symptoms appear to be more common following vaccination. To c...
America Out Loud - Our show this week is an excerpt from the BS Free MD Podcast, where Drs. May and Tim Hindmarsh speak with cardiologist and internist Dr. Peter McCullough, a leading scientist investigating long COVID and post-vaccine syndromes. The conversation dives into the evolving understanding of spike-protein–related illness, McCullough’s ground-breaking research linking persistent spike protein exposure to long-term disability, and his practical “McCullough Protocol-Based Spike Detoxification” approach. Dr. May Hindmarsh shares her personal struggle: after severe COVID infections, menopause, and hormonal treatment, her health deteriorated—with rapid heart rate, mast-cell activation, histamine sensitivity, anxiety, insomnia, and gastrointestinal distress. She later discovered her blood test showed sky-high anti–spike protein antibody levels (>12,000 U/mL on LabCorp testing). McCullough explains that such titers correlate with circulating spike protein fragments, even years ...
Reviewed by: OneDayMD Editorial Team | Last updated: July 16, 2026 (includes link to Dr Paul Marik and Dr Justus Hope latest Substack article related to "turbo cancer") COVID-19 vaccines and boosters — both mRNA and non-mRNA — pose an increased risk of six types of cancer and a 27% higher risk of cancer overall , according to a recent South Korean study of over 8 million people. Four South Korean researchers published the report last week as a letter in Biomarker Research, a Springer Nature journal. According to the study, COVID-19 vaccines and boosters are associated with a higher risk of breast, colorectal, gastric, lung, prostate and thyroid cancer, across all vaccine types and age groups. Mainstream medical commentators were quick to dismiss the findings, with MedPageToday describing it as “flawed.” But other medical and scientific experts disagreed. “In plain terms: both major COVID-19 vaccine platforms ...
The McCairn Protocol (Edogawa–McCairn Protocol): Overview and Mechanistic Rationale The McCairn Protocol (also referred to as the Edogawa–McCairn Protocol ) is an experimental, two-phase treatment approach promoted by Kevin McCairn in collaboration with Edogawa Hospital. It is primarily proposed for individuals with Long COVID and post-mRNA vaccine–associated syndromes , targeting hypothesized drivers such as persistent spike protein, amyloid-like fibrin microclots, autoantibodies, chronic inflammation, and associated vascular or neurological dysfunction. Phase 1: Double Filtration Plasmapheresis (DFPP) / Plasma Adsorption (“Cleansing”) Double Filtration Plasmapheresis (DFPP) is a specialized form of therapeutic apheresis currently used in parts of Asia, including Japan, for selected autoimmune, neurological, and metabolic conditions. Procedure Blood is withdrawn, often via a large-bore catheter (e.g., internal jugular access). It is passed through a dual-filtration syste...
⚠ Medical Disclaimer — Please Read First This article is for educational and historical reference only and does not constitute medical advice, diagnosis, or treatment. It describes a COVID-19 outpatient protocol first proposed in 2020 by the late Dr. Vladimir Zelenko, alongside what current clinical research (through 2026) shows about each component . Hydroxychloroquine and ivermectin are prescription-relevant medicines with real drug interactions and side effects; large randomized trials completed since 2021 have not shown a meaningful treatment benefit for COVID-19 (details below), and neither drug is recommended for this use by the FDA, WHO, or NIH COVID-19 Treatment Guidelines. Always consult a licensed physician before starting any supplement or medication regimen , especially if you are pregnant or breastfeeding, have a cardiac, kidney, or thyroid condition, or take other prescription medications. For a virtual consultation with a physician, visit The Wellness Company . ...
Introduction The rapid development and deployment of COVID-19 vaccines have been monumental in combating the global pandemic, saving countless lives and enabling societies to regain a sense of normalcy. Central to the efficacy of many of these vaccines, particularly mRNA and viral vector-based ones, is the spike protein—a key component of the SARS-CoV-2 virus that facilitates its entry into human cells. By instructing the body to produce a version of this protein, vaccines train the immune system to recognize and neutralize the virus without causing illness. However, as vaccination campaigns expanded, so did public curiosity and concern about the spike protein's role, fueled by a mix of scientific complexity, misinformation, and distrust. For years, the public was told that COVID-19 mRNA vaccine components degraded rapidly—within days to weeks. Hulscher, McCullough, and colleagues' 2026 peer-reviewed study challenges that assumption, reporting findings ...
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