In this breaking interview, Dr. Takuji Shirasawa from the Ochanomizu Health and Longevity Clinic describes a 60-year old Japanese man who took 4 Pfizer COVID-19 vaccines and presented with a loss of mental clarity otherwise known as “brain fog.” Shirasawa used MR angiography to demonstrate sessile bilateral arterial thrombi in the carotid bulbs. His hypothesis was that mini-blood clots may be responsible for the neurological and cognitive symptoms.
Shirasawa performed a N-of-1 trial giving the patient a complex blend of oral proteolytic and thrombolytic enzymes featuring nattokinase, bromelain, serrapeptase, and papain adding over a dozen natural ingredients given in proprietary blends from Texas based Phytomedic Labs. The patient was also administered aspirin 100 mg per day.
Serial d-dimer levels showed a spike in concentration as the blood clots were lysed and shown to resolve over serial MR angiographic scans with virtual angioscopy. As the blood clots disappeared the patient’s brain fog lifted. I can tell you as a cardiologist these images are stunning.
First-in-man reports are very important in medicine. Such reports for coronary angioplasty and stenting changed medical history. Dr. Shirasawa’s case may have a similar historical impact as the medical community is even better supported with the mechanistic rationale for McCullough Protocol Base Spike Detoxification and even more intensive protocols in the future.
Base Spike Detox According to Dr Peter McCullough (in a X/Twitter post): Base Spike Detox is what I am currently using in my practice for those who have had COVID-19 multiple times, one or more of the COVID-19 vaccines, or both and believe persistent SARS-CoV-2 Spike protein could be causing problems in their body. I have arrived, based on the emerging scientific literature (1) and my clinical observation, that three OTC products are essential as a triple base combination: Nattokinase 2000 FU (100 mg) twice a day — take on an empty stomach Bromelain 500 mg once a day — take on an empty stomach Nano/Liposomal Curcumin 500 mg twice a day — take with food How long should I take this? Dr. McCullough recommends a minimum of 3 months , with many patients requiring 6–12 months or longer. Progress can be tracked via a spike protein antibody test (available through Labcorp in m...
Can you remove spike proteins from your body? Dr. Paul Marik and Dr. Pierre Kory are pleased to introduce the I-RECOVER: Post-Vaccine Treatment protocol, designed to help people who have experienced adverse symptoms after a COVID vaccine. Kory and Marik are both part of the FLCCC*, which was founded in 2020 to share early treatment protocols for COVID-19. Kory is an ICU specialist, triple board certified in internal medicine, critical care and pulmonary medicine. He now runs a private tele-health practice specializing in the treatment of COVID-19, so-called "long-COVID" and post-vaccine syndrome. *The FLCCC Alliance is now the Independent Medical Alliance Note that there are significant overlaps between the symptoms and features of long COVID/long-hauler syndrome and post-vaccine syndrome. However, a number of clinical features appear to be characteristic of post-vaccine syndrome; most notably, severe neurological symptoms appear to be more common following vaccination. To c...
Dr. McCullough explained (1) that the spike protein is an engineered, synthetic molecule roughly 1,200 amino acids long and resistant to degradation by the body’s normal proteases. He described how the protein was modified in laboratory settings (notably at the Wuhan Institute of Virology) to tightly bind to the ACE2 receptor, which is found throughout the body—in the lungs, heart, endothelium, kidneys, and brain. Because this receptor regulates angiotensin metabolism, older individuals with fewer ACE2 sites catabolize the spike less efficiently, leading to worse outcomes. Whether introduced by infection or by genetic‑code‑based vaccines, McCullough asserted, the persistent spike damages tissues directly and through chronic inflammation, micro‑clotting, and autoimmune cross‑reactivity. He cited more than 300 papers documenting spike deposits in the heart, brain, and vascular tissue, relating these findings to post‑vaccine myocarditis, strokes, and clotting disorders. A chief diagnostic...
The McCairn Protocol (Edogawa–McCairn Protocol): Overview and Mechanistic Rationale The McCairn Protocol (also referred to as the Edogawa–McCairn Protocol ) is an experimental, two-phase treatment approach promoted by Kevin McCairn in collaboration with Edogawa Hospital. It is primarily proposed for individuals with Long COVID and post-mRNA vaccine–associated syndromes , targeting hypothesized drivers such as persistent spike protein, amyloid-like fibrin microclots, autoantibodies, chronic inflammation, and associated vascular or neurological dysfunction. Phase 1: Double Filtration Plasmapheresis (DFPP) / Plasma Adsorption (“Cleansing”) Double Filtration Plasmapheresis (DFPP) is a specialized form of therapeutic apheresis currently used in parts of Asia, including Japan, for selected autoimmune, neurological, and metabolic conditions. Procedure Blood is withdrawn, often via a large-bore catheter (e.g., internal jugular access). It is passed through a dual-filtration syste...
Treatment should start based on clinical suspicion as soon as possible, preferably within the first 3 days of symptoms. Perform PCR testing, but do not withhold treatment pending results. 'Early' treatment will make significant difference in outcome as opposed to late treatment. Related: How can I get Ivermectin? See the directory of professionals in US below. Directory of Doctors (by State) Prescribing Effective Outpatient COVID-19 Therapy USA MULTIPLE STATES (Telemedicine or online consultation) The Wellness Company ( twc.health ) Medical Specialty: Family Medicine, Functional Medicine Supported Protocols: I-PREVENT (COVID Protection), I-CARE (Early at-home treatment), I-RECOVER (Long COVID and Post-Vaccine treatment) Dr. Miguel Antonatos (IVM) (855) 767-8559 https://text2md.com (States: AL, AZ, CO, FL, GA, IA, ID, IL, KS, KY, MD, ME, MI, MN, MS, ND, NE, NJ, NV, OK, SC, SD, TN, UT, VT, WA, WI, WV) ...
Dr. Peter McCullough is an internist, cardiologist, epidemiologist, a full professor of medicine at Texas A&M College of Medicine in Dallas, USA. He also has a master's degree in public health and is known for being one of the top five most-published medical researchers in the United States and is the editor of two medical journals. McCullough Protocol 2022 Update: Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections: A Phase 2 Randomized Clinical Trial ( JAMA 2025 ) Everyone is familiar with nasal and oral swab testing for COVID-19. It should be obvious the virus is replicating in the nose, and with Omicron, the speed of replication has become much greater than the prior strains of the virus. Thus, there is a wonderful opportunity to reduce viral replication, in fa...
A clinician-developed regimen of nattokinase, bromelain, and curcumin for clearing persistent SARS-CoV-2 spike protein — with dosing, safety guidance, monitoring, and full FAQ. Editorial Team | Originally published March 2023 | Last updated December 30, 2025 | Reviewed against published literature and Dr. McCullough's 2025 clinical updates ⚠️ Medical Disclaimer — Please Read First This article is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. The Base Spike Detox protocol involves supplements with significant anticoagulant activity. Always consult a licensed physician before starting , especially if you are taking blood thinners, are pregnant or breastfeeding, have a bleeding disorder, or are treating a child. For a virtual consultation with a physician familiar with this protocol,...
A fast-spreading Ebola outbreak in the DRC's Ituri province has killed at least 87 people across 246 suspected cases — and experts warn the Bundibugyo strain driving it has no approved vaccine. By One Day MD Editorial Team · Updated May 17, 2026 · 6 min read 87+ Deaths confirmed 246 Suspected cases 13 Lab-confirmed cases 0 Approved vaccines A deadly Ebola outbreak has been confirmed in the Democratic Republic of Congo (DRC), health authorities announced on May 15, 2026 — and it is already spreading beyond the country's borders. At least 87 people have died and 246 suspected cases have been recorded in Ituri province, eastern DRC, making this the country's 17th Ebola outbreak since the virus was first identified there in 1976. What makes this outbreak uniquely alarming is the strain involved. Unlike the majority of Congo's previous outbreaks — which were caused by the well...
Over the last three years, the COVID-19 pandemic has transformed almost every aspect of our lives before we've had time to stop and question it. Although no official definition exists for post-COVID-vaccine syndrome, a temporal correlation between a patient receiving a COVID-19 vaccine and beginning or worsening of clinical manifestations is sufficient to diagnose as a COVID-19 vaccine-induced injury, when the symptoms are unexplained by other concurrent causes. Dr. Paul Marik and Dr. Pierre Kory are pleased to introduce the I-RECOVER: Post-Vaccine Treatment protocol, designed to help people who have experienced adverse symptoms after a COVID vaccine. Kory and Marik are both part of the FLCCC ( The FLCCC Alliance is now the Independent Medical Alliance ), which was founded in 2020 to share early treatment protocols for COVID-19. Kory is an ICU specialist, triple board certified in internal medicine, critical care and pulmonary medicine. He now runs a priva...
On 2 May 2026, a cluster of passengers with severe respiratory illness aboard a cruise ship was reported to the World Health Organization (WHO). The vessel was carrying 147 passengers and crew members. As of 4 May 2026, seven cases — including two laboratory-confirmed hantavirus infections and five suspected cases — had been identified. Among these cases were three deaths, one critically ill patient, and three individuals with mild symptoms. Illness onset occurred between 6 and 28 April 2026 and was characterized by fever, gastrointestinal symptoms, rapid progression to pneumonia, acute respiratory distress syndrome (ARDS), and shock. Further investigations remain ongoing. The outbreak response includes coordinated international public health measures such as in-depth epidemiological investigations, case isolation and medical care, patient evacuation, and laboratory testing. Human hantavirus infection is primarily acquired through contact with the urine, feces, or saliva of infected ro...
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