Independent COVID-19 Guides, Resources and Protocols - Reducing Risk of COVID-19 Infection and Severity
Dr Peter McCullough: Spike Protein Exhausts Cardiomyocyte Mitochondria
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One of the most common features of long-COVID syndrome is post-exertional malaise. Even athletes tell me the smallest workout leaves them completely spent, unable to function for several hours.
Nakahara et al demonstrated that the hearts of those vaccinated almost always have abnormal PET scans demonstrating a shift from free fatty acids to 18-flourodeoxyglucose indicative of a fundamental cellular change that has occurred as a result of the vaccine Spike protein. The subcellular organelle responsible for energy generation is the mitochondria.
Van Huynk et al have demonstrated in cultured human cardiomyocytes, that the S1 segment of the Spike protein at 72 hours essentially exhausts the mitochondria. These subcellular organelles become fatigued, change their molecular functions, and even begin to undergo fission into fragments. No wonder people feel so bad all over with long-COVID!
Huynh TV, Rethi L, Lee TW, Higa S, Kao YH, Chen YJ. Spike Protein Impairs Mitochondrial Function in Human Cardiomyocytes: Mechanisms Underlying Cardiac Injury in COVID-19. Cells. 2023 Mar 11;12(6):877. doi: 10.3390/cells12060877. PMID: 36980218; PMCID: PMC10046940.
We understand that McCullough Protocol Base Spike Detoxification is essential in treating long-COVID allowing cells to recover normal mitochondrial function. Those with very high Spike concentrations reflected by elevated Spike antibody titers > 1000 units/ml (Roche Elecsys assay) will likely require a full year or more of detoxification.
While undergoing this process, a supplement Dr Peter McCullough commonly recommend to address the symptoms of long-COVID including lack of energy and post-exertional malaise is Elevated Energy from The Wellness Company. If well tolerated, two capsules twice a day can be taken as empirically. While no therapeutic claims can be made, it is reasonable to consider this product for a boost in energy that will help on the road to recovery.
Base Spike Detox According to Dr Peter McCullough (in a X/Twitter post): Base Spike Detox is what I am currently using in my practice for those who have had COVID-19 multiple times, one or more of the COVID-19 vaccines, or both and believe persistent SARS-CoV-2 Spike protein could be causing problems in their body. I have arrived, based on the emerging scientific literature (1) and my clinical observation, that three OTC products are essential as a triple base combination: Nattokinase 2000 FU (100 mg) twice a day Bromelain 500 mg once a day Nano/Liposomal Curcumin 500 mg twice a day Related: Nattokinase, Bromelain and Curcumin from The Wellness Company Additional products can be added, including NAC, IVM (Ivermectin), HCQ (Hydroxychloroquine), fluvoxamine, low-dose naltrexone, and blood thinners, depending on the clinical evaluation and the syndrome. The therapeut...
Over the last three years, the COVID-19 pandemic has transformed almost every aspect of our lives before we've had time to stop and question it. Although no official definition exists for post-COVID-vaccine syndrome, a temporal correlation between a patient receiving a COVID-19 vaccine and beginning or worsening of clinical manifestations is sufficient to diagnose as a COVID-19 vaccine-induced injury, when the symptoms are unexplained by other concurrent causes. Dr. Paul Marik and Dr. Pierre Kory are pleased to introduce the I-RECOVER: Post-Vaccine Treatment protocol, designed to help people who have experienced adverse symptoms after a COVID vaccine. Kory and Marik are both part of the FLCCC (The FLCCC Alliance is now the Independent Medical Alliance ), which was founded in 2020 to share early treatment protocols for COVID-19. Kory is an ICU specialist, triple board certified in internal medicine, critical care and pulmonary medicine. He now runs a privat...
The Front Line COVID-19 Critical Care (FLCCC) Alliance was initially formed as a working group during the early COVID-19 pandemic days in response to multiple early reports of COVID patients with an inexplicably high need for prolonged mechanical ventilation and an excessive death rate. Based on rapidly emerging clinical trials evidence, the FLCCC team has developed the I-MASK+ protocol ( is now divided into I-Prevent and I-Care protocols ) for prophylaxis and at home treatment of early stage COVID-19. Quercetin, zinc and a number of nutrients and drugs are part of this protocol, not only for critical care but also for prophylaxis and mild disease being treated at home. This article, we will dive deeper to provide the scientific background, related references and rationale of the FLCCC protocols. FLCCC ( Front Line COVID-19 Critical Care) Protocols I-MASK+ Prevention & Early Outpatient Treatment Protocol for COVID-19 was designed for use as a prevention and...
Can you remove spike proteins from your body? Dr. Paul Marik and Dr. Pierre Kory are pleased to introduce the I-RECOVER: Post-Vaccine Treatment protocol, designed to help people who have experienced adverse symptoms after a COVID vaccine. Kory and Marik are both part of the FLCCC, which was founded in 2020 to share early treatment protocols for COVID-19. Kory is an ICU specialist, triple board certified in internal medicine, critical care and pulmonary medicine. He now runs a private tele-health practice specializing in the treatment of COVID-19, so-called "long-COVID" and post-vaccine syndrome. Note that there are significant overlaps between the symptoms and features of long COVID/ long-hauler syndrome and post-vaccine syndrome. However, a number of clinical features appear to be characteristic of post-vaccine syndrome; most notably, severe neurological symptoms appear to be more common following vaccination. To complicate matters further, patients with long COVID are ofte...
Please enjoy this continuing medical education lecture delivered at 40th Cellular Detoxification Conference sponsored by International College of Integrative Medicine in Indianapolis, Indianana, on September 7, 2024. There are no medicine grand rounds or primary care conferences addressing this topic. It is a white space in medicine where no academic medical center has a fundamental approach to handling about 5-10% of the population suffering from post-acute sequalae after recurrent SARS-CoV-2 infection or COVID-19 infection. Both load the body with pathogenic Spike protein which incites inflammation, oxidative stress, coagulation, and all the downstream effects that result in symptoms. BSD=Base Spike Detoxification Because I have taken the ultimate accountability for McCullough Protocol Base Spike Detoxification (BSD) by publishing and copyrighting it in my own name, I can tell you first hand I get feedback about perceived safety and efficacy on a regular basis from all ov...
Treatment should start based on clinical suspicion as soon as possible, preferably within the first 3 days of symptoms. Perform PCR testing, but do not withhold treatment pending results. 'Early' treatment will make significant difference in outcome as opposed to late treatment. Related: How can I get Ivermectin? See the directory of professionals in US below. Directory of Doctors (by State) Prescribing Effective Outpatient COVID-19 Therapy USA MULTIPLE STATES (Telemedicine or online consultation) The Wellness Company ( twc.health ) Medical Specialty: Family Medicine, Functional Medicine Supported Protocols: I-PREVENT (COVID Protection), I-CARE (Early at-home treatment), I-RECOVER (Long COVID and Post-Vaccine treatment) Dr. Miguel Antonatos (IVM) (855) 767-8559 https://text2md.com (States: AL, AZ, CO, FL, GA, IA, ID, IL, KS, KY, MD, ME, MI, MN, MS, ND, NE, NJ, NV, OK, SC, SD, TN, UT, VT, WA, WI, WV) ...
Dr. Peter McCullough is an internist, cardiologist, epidemiologist, a full professor of medicine at Texas A&M College of Medicine in Dallas, USA. He also has a master's degree in public health and is known for being one of the top five most-published medical researchers in the United States and is the editor of two medical journals. McCullough Protocol 2022 Updates: Double blind randomized controlled trial of saline solution gargling and nasal rinsing in COVID infection (Nov 2023) What really killed COVID-19 patients: It wasn't a cytokine storm, suggests study (2023) Everyone is familiar with nasal and oral swab testing for COVID-19. It should be obvious the virus is replicating in the nose, and with Omicron, the speed of replication has become much greater than the pr...
Early treatment is critical and the most important factor in managing this disease. COVID-19 is a clinical diagnosis; a confirmed antigen or PCR test is not required. Treatment should be initiated immediately after the onset of flu-like symptoms. The multiple therapies and drugs in this protocol have different mechanisms of action and work synergistically during various phases of the disease. About I-CARE Protocol The information in this document is our recommended approach to COVID-19 based on the best (and most recent) literature. It is provided as guidance to healthcare providers worldwide on the early treatment of COVID-19. Patients should always consult with their provider before starting any medical treatment. Updates: Ivermectin, Hydroxychloroquine Use Soared During COVID-19 Pandemic: 2025 Study 53,000+ Patient Study Finds Low-Dose Hydroxychloroquine Associated with Reduced COVID-19 Mortality in China (Frontiers of Medicine 2025) New medications may be added and/or changes ...
Well-respected North Texas cardiologist, Dr. Peter McCullough has impeccable academic credentials. He's an internist, cardiologist, epidemiologist, a full professor of medicine at Texas A&M College of Medicine in Dallas. He also has a master's degree in public health and is known for being one of the top five most-published medical researchers in the United States and is the editor of two medical journals. McCullough et al. Reviews in Cardiovascular Medicine, 2020 McCullough Protocol 2022 Updates: How to Detox Spike Protein from Body (November 2023) Use of hydroxychloroquine in multidrug protocols for SARS-CoV-2 (October 2024) Paxlovid for Vaccinated or Unvaccinated Adult Outpatients with ...
BY THOMAS E. LEVY, MD, JD As the acute cases of COVID have continued to decline, the prevalence of the Persistent Spike Protein (PSP) syndrome has continued to increase. The spike protein is that part of the COVID pathogen that attaches to ACE2 receptors throughout the body and permits the entry of the entire virus into the newly infected cell. There appear to be no cells, tissues, or organs in the body that are completely spared from this PSP attack once enough of it has been introduced into the body. The many mechanisms of action involved in the ultimate removal of spike protein. The persistent presence of the spike protein has been shown to be secondary to the inability to completely resolve a bout of COVID (chronic COVID or long-haul COVID) as well as the spike protein exposure from mRNA inoculation(s). And as more time has passed, the PSP syndrome following one or more mRNA shots has emerged as the most common reason for PSP, especially following a booster injection. Not surprisi...
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