Children Vaccinated in Messenger RNA COVID-19 Trials at Higher Risk of Certain Illnesses: Study
Compared to placebo recipients, children who received one of the modified messenger ribonucleic acid (mRNA) shots were at an increased risk for serious adverse events or respiratory tract infections, Dr. Christine Stabell Benn and other researchers found.
Dr. Benn led a group in analyzing data from phase 3 trials conducted for the mRNA vaccines in children, or people younger than 18.
They examined trial data from regulatory websites and other sources, ending up with six studies that covered 25,549 people, about 68 percent of whom received a vaccine. The rest received a placebo.
Moderna and Pfizer trials divided children into slightly different age groups. Moderna often grouped kids 6 months to 11 years of age, while Pfizer did so for children aged 5 months to 11. The researchers looked at outcomes across all children, and also after stratifying children by young, younger, and oldest.
The risk of serious adverse events, or events leading to death or hospitalization, was worse for younger and oldest recipients, but not for the youngest. The 12- to 17-year-olds also faced an increased risk of severe adverse events, or events deemed medically significant but not immediately life-threatening. That higher risk was not statistically significant in the younger group, and the risk was lower in the youngest group.
The youngest children, however, faced a higher risk of respiratory tract infections such as bronchitis and respiratory syncytial virus. Respiratory tract infections were not counted in the trials of younger and oldest children.
The researchers also found that vaccinated children were also at higher risk of skin and tissue disorders.
The analysis did have a favorable conclusion when it came to preventing COVID-19 itself. The vaccines decreased the risk of infection, although when stratified by age the decreased risk was only statistically significant for children aged 2 to 5 who received a Moderna vaccine.
"The most important finding is that when we compile the data from the phase 3 trials, some clear signals emerge—the vaccines reduced the risk of COVID-19, but they at the same time increased the risk of severe adverse events, particularly in the older children who also received the highest vaccine doses, and they increased the risk of lower respiratory tract infections in the younger children for whom this information was collected," Dr. Benn told The Epoch Times in an email.
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