Immune Systems Advisor

Broad Killing Power Against H5, H7 and H9 Avian Influenza A Viruses with Nasal and Throat Sprays A new outbreak of H7N9 avian influenza in the U.S ., has been detected on a farm of 47,654 commercial broiler breeder chickens in Noxubee, Mississippi, March 13, 2025, as the Paris-based World Animal Health Organisation said in a report on Monday, citing U.S. Authorities. H7N9 is thought to be considerably more deadly than H5N1. I wondered if standard-of-care nasal and throat sprays and gargles with dilute povidone iodine would continue to have protective effects. Hiroshi Ito, Toshihiro Ito, Muneo Hikida, Junko Yashiro, Akira Otsuka, Hiroshi Kida, Koichi Otsuki; Outbreak of Highly Pathogenic Avian Influenza in Japan and Anti-Influenza Virus Activity of Povidone-Iodine Products. Dermatology 1 February 2006; 212 (Suppl. 1): 115–118. https://doi.org/10.1159/000089210 Ito et al reported in in 2006: The in vitro antiviral activity of PVP-I products (2% PVP-I solution, 0.5% PVP-I scrub, 0.25% PV...

By Nicolas Hulscher, MPH and Peter A. McCullough, MD, MPH In addressing the H5N1 bird flu outbreak, public health measures should emphasize accessible preventive solutions, such as iodine-based nasal sprays and gargles, which hold promise in preventing zoonotic avian influenza transmission and human infection. Regular use of iodine nasal sprays by farmers, poultry workers, and veterinarians could help reduce viral carriage in the upper respiratory tract, lowering the risk of infection from direct animal exposure. Sriwilaijaroen et al conducted a preclinical study of influenza virus strains on chicken egg cells and demonstrated that dilute povidone iodine (PVP-I) was effective at neutralizing the two pathogenic parts of the influenza virus—hemagglutinin (binding) and sialidase (catalytic hydrolysis). Of note, these effects were complimentary to the modest effect of oseltamivir (Tamiflu) in these experiments.  As we outlined in a recent article , iodine-based antiseptics should al...

CofixRx Nasal Spray was developed by a board-certified anesthesiologist with the assistance and advisory information of seven other physicians. They also worked with a compounding pharmacist and pharmaceutical-grade manufacturer. The initial formula was tested at Utah State University Institute of Antiviral Research and found to have amazing (95% or greater) antiviral properties against SARS-CoV-2, Delta, Omnicron, Influenza, Rhinovirus (common cold), RSV, and HRV 14. The spray lasts for hours in the nasal passages because of another special characteristic of the product’s ingredients. The ingredients also create a polysaccharide solution, which is a mucoadhesive. The mucoadhesive does three things. It creates a physical barrier to prevent viruses, bacteria, and allergens (like pet dander, pollen, mold spores, etc.) from adhering to and irritating the mucous membrane. Then, it allows the povidone-iodine to NOT get absorbed for hours, keeping it on the surface of the nasal passages wh...

Almost every year, it seems a pandemic is hyped up. I would argue that's because: They give federal agencies (e.g., the CDC) a way to justify their necessity and get Congressional funding. The media thrives off of hooking the public through fear and appeasing its sponsors (e.g., the pharmaceutical industry). It sustains a biodefense industry that uses fear to get a lot of money (e.g., 27.7 billion dollars in 20231) to "prevent" pandemics. Tackling many of the real health issues facing our country requires confronting the vested interests responsible for them and addressing the underlying causes of chronic illnesses in the country. In contrast, going to war against a disease is far easier and receives minimal pushback but allows the government to present the facade of safeguarding our health. As such, we will frequently see a myriad of dubious pandemic preventatives be pushed on us (2) (e.g., the mass slaughter of livestock, the newest "emergency" vaccine, or ine...