The COVID Advisor

There’s no evidence that IVM works? There are no randomised controlled trials of IVM? The withdrawn study nullifies the conclusions of the meta-analyses of IVM? Most of the studies on ivermectin are small and are of low quality? We shall wait for bigger and better quality evidence before we can make formal recommendations? The above are answers that you may have read from various media channels.  While we carefully lay out the evidence in this article, we leave it up to you, the reader, to decide whether ivermectin is effective or not.  That said, always consult your trusted medical professional before you take any medication or supplement. Do not self-medicate. This article, we will dive deeper to provide the scientific background, related references, updated references and rationale of ivermectin in COVID-19. Summary of the Evidence for Ivermectin in COVID-19 Ivermectin is an anti-parasite medicine whose discovery won the Nobel Prize in 2015 for its impacts in ridding large ...

Standard doses of ivermectin (0.2 mg/kg x 1–2 days) have a nearly unparalleled safety profile historically among medicines as evidenced by the following findings:  WHO Guidelines for Scabies: “the majority of side effects are minor and transient”  Prof Jacques Descotes, Toxicologist, Expert on Safety of Ivermectin: “severe adverse events are unequivocally and exceedingly rare”  LiverTox Database: Not considered toxic to the liver  Nephrotox Database- Not considered toxic to the kidney  PneumoTox: Not considered toxic to the lungs Safety of High Dose Ivermectin  In COVID-19, particularly in regard to the emerging variants of concern, viral loads are higher and viral replication is thought to be prolonged. Given that ivermectin has demonstrated a strongdose-response relationship in terms of viral clearance, higher doses have not only been required, but have demonstrated clinical efficacy. Below are hyperlinked references to numerous studies demonstrating the...